Influence of Liposomes and Niosomes on the In Vitro Permeation and Skin Retention of Finasteride

    March 2005 in “ Iranian Journal of Pharmaceutical Sciences ”
    Saeid Daneshamouz, M. Tabakhian, Naser Tavakoli, Mohammad Jafari
    Studysummary This study demonstrated that liquid-state vesicles may reduce the absorption of finasteride through the skin while increasing its concentration and retention in the dermis layer in hamster models.
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    Research cited in this study 15

    1. Hirsutism and Acne in Polycystic Ovary Syndrome Baillière's best practice & research. Clinical obstetrics & gynaecology/Baillière's best practice and research in clinical obstetrics and gynaecology · 2004
    2. Use of Finasteride in the Treatment of Men With Androgenetic Alopecia Journal of Investigative Dermatology Symposium Proceedings · 2003
    3. Transfollicular Drug Delivery: Penetration of Drugs Through Human Scalp Skin and Comparison of Penetration Between Scalp and Abdominal Skins In Vitro Journal of drug targeting · 2002
    4. Treatments for Androgenetic Alopecia and Alopecia Areata Drugs · 2001
    5. The Effects of Finasteride on Scalp Skin and Serum Androgen Levels in Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1999
    6. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998
    7. Importance of Sebaceous Glands in Cutaneous Penetration of an Antiandrogen: Target Effect of Liposomes Journal of Pharmaceutical Sciences · 1997
    8. Topical Finasteride in the Treatment of Androgenic Alopecia: Preliminary Evaluations After a 16-Month Therapy Course Journal of Dermatological Treatment · 1997
    9. Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP-Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor Journal of the American Chemical Society · 1996
    10. The 5 Alpha-Reductase System and Its Inhibitors Dermatology · 1996
    11. Percutaneous Absorption of a New Antiandrogen Included in Liposomes or in Solution International Journal of Pharmaceutics · 1995
    12. Local and Systemic Reduction by Topical Finasteride or Flutamide of Hamster Flank Organ Size and Enzyme Activity Journal of Investigative Dermatology · 1995
    13. A Prospective Randomized Trial Comparing Finasteride to Spironolactone in the Treatment of Hirsute Women The Journal of Clinical Endocrinology and Metabolism · 1995
    14. Clinical and Hormonal Effects of the 5 Alpha-Reductase Inhibitor Finasteride in Idiopathic Hirsutism The Journal of Clinical Endocrinology and Metabolism · 1994
    15. The Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Scalp Skin Testosterone and Dihydrotestosterone Concentrations in Patients with Male Pattern Baldness The Journal of Clinical Endocrinology and Metabolism · 1994

    Related research 4

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    2. Effect of Charge Carrier Lipid on Skin Penetration, Retention, and Hair Growth of Topically Applied Finasteride-Containing Liposomes Biomolecules & Therapeutics · 2011
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