Hirsutism and Acne in Polycystic Ovary Syndrome

    Johanna S. Archer, R. Jeffrey Chang
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    TLDR Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.
    Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of reproductive age, with a prevalence of 5-10%. It is characterized by symptoms such as hyperandrogenism, chronic anovulation, insulin resistance, and infertility, with hyperandrogenism often presenting as hirsutism and acne. Treatments for these symptoms include oral contraceptive pills (OCPs), antiandrogens like spironolactone, flutamide, and finasteride, and topical medications. Recent studies have indicated that lower doses of these treatments are as effective as higher doses, offering the benefits of reduced costs and fewer side effects. Despite their cosmetic appearance, hirsutism and acne can lead to significant social and emotional distress, and it is important for physicians to address these issues with empathy and care.
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