Polycystic Ovary Syndrome: Special Diagnostic and Therapeutic Considerations for Children

March 2015 in “ Pediatric Dermatology ”

Faranak Kamangar, Batool Okhovat, Timothy H. Schmidt, B S Abram Beshay, Lauri A. Pasch, Marcelle I. Cedars, Heather G. Huddleston, Kanade Shinkai

Polycystic Ovary Syndrome PCOS hyperandrogenism oligomenorrhea polycystic ovaries insulin resistance endometrial cancer cardiovascular events Rotterdam criteria

Studysummary This review discusses diagnostic and management challenges of polycystic ovary syndrome in children and adolescents and reports no new clinical results; it emphasizes early intervention when a provisional diagnosis is suspected.

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Research cited in this study

11 / 11 results

Age-Related Differences in the Reproductive and Metabolic Implications of Polycystic Ovarian Syndrome: Findings in an Obese, United States Population

research Age-Related Differences in the Reproductive and Metabolic Implications of Polycystic Ovarian Syndrome: Findings in an Obese, United States Population

16 citations , April 2012 in “Gynecological Endocrinology”

This study found that older women with polycystic ovarian syndrome are more likely to experience metabolic syndrome and have different metabolic and reproductive profiles than younger women.

research The Diagnosis of Polycystic Ovary Syndrome in Adolescents

212 citations , May 2010 in “American Journal of Obstetrics and Gynecology”

This article suggests using only firm criteria to diagnose polycystic ovary syndrome in adolescents, due to the evolving nature of its features during this period.

research Clinical and Endocrine Characteristics of the Main Polycystic Ovary Syndrome Phenotypes

145 citations , March 2010 in “Fertility and Sterility”

This study reported that ovulatory PCOS is a milder form of the condition compared to classic PCOS phenotypes, which share similar clinical and hormone characteristics.

Specific Dermatologic Features of Polycystic Ovary Syndrome and Its Association with Biochemical Markers of Metabolic Syndrome and Hyperandrogenism

research Specific Dermatologic Features of Polycystic Ovary Syndrome and Its Association with Biochemical Markers of Metabolic Syndrome and Hyperandrogenism

67 citations , February 2010 in “Acta Obstetricia et Gynecologica Scandinavica”

In this study, hirsutism in women with PCOS was strongly associated with hyperandrogenism and metabolic abnormalities, while acne and androgenic alopecia were not effective markers for hyperandrogenism.

research Acne and Systemic Disease

76 citations , November 2009 in “Medical Clinics of North America”

This article reviews the hormonal and medication-related factors associated with acne development but does not present new research findings.

research Prevalence of Hyperandrogenemia in Polycystic Ovary Syndrome Diagnosed by the National Institutes of Health 1990 Criteria

118 citations , February 2009 in “Fertility and Sterility”

This study found that approximately 75% of women with PCOS exhibited hyperandrogenemia, with free testosterone being the most frequently elevated marker.

research Polycystic Ovary Syndrome: Comprehensive Overview and Diagnostic Criteria

989 citations , August 2007 in “The Lancet”

This article reviews the clinical features, diagnostic criteria, and possible genetic and environmental influences of polycystic ovary syndrome but provides no new research findings.

research Acne: Hormonal Concepts and Therapy

118 citations , September 2004 in “Clinics in Dermatology”

This review discusses the role of hormones in acne vulgaris and highlights the need for further research on their mechanisms of action; it reports no new clinical results.

research Hirsutism and Acne in Polycystic Ovary Syndrome

169 citations , August 2004 in “Baillière's best practice & research. Clinical obstetrics & gynaecology/Baillière's best practice and research in clinical obstetrics and gynaecology”

This article discusses treatments for hirsutism and acne in women with polycystic ovary syndrome, suggesting that lower doses of current medications maintain efficacy while reducing cost and side effects, but reports no new clinical results.

research Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome

4809 citations , January 2004 in “Fertility and Sterility”

This review discusses polycystic ovary syndrome, emphasizing its broad range of manifestations and associations with risks like type 2 diabetes and cardiovascular events, but reports no new clinical results.

research Developmental Origin of Polycystic Ovary Syndrome: A Hypothesis

430 citations , July 2002 in “Journal of Endocrinology”

This hypothesis paper suggests that PCOS may result from genetically determined ovarian hypersecretion of androgens, influencing hormone regulation and insulin resistance, with obesity further affecting its severity; no new clinical results are reported.