Solid Effervescent Formulations as a New Approach for Topical Minoxidil Delivery

    October 2016 in “ European Journal of Pharmaceutical Sciences ”
    Maíra N. Pereira, Heidi Luise Schulte, Natane C.B. Duarte … Angel Concheiro
    Studysummary This study found that a novel effervescent formulation significantly increased minoxidil sulphate accumulation in hair follicles and skin compared to a standard minoxidil solution.
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    Research cited in this study 11

    1. Iontophoresis of Minoxidil Sulphate Loaded Microparticles: A Strategy for Follicular Drug Targeting? Colloids and Surfaces B: Biointerfaces · 2015
    2. Chitosan Nanoparticles for Targeting and Sustaining Minoxidil Sulphate Delivery to Hair Follicles International Journal of Biological Macromolecules · 2015
    3. Self-Assembled Polymeric Nanocarriers for the Targeted Delivery of Retinoic Acid to the Hair Follicle Nanoscale · 2015
    4. Iontophoresis-Targeted, Follicular Delivery of Minoxidil Sulfate for the Treatment of Alopecia Journal of Pharmaceutical Sciences · 2013
    5. Chitosan Microparticles for Sustaining the Topical Delivery of Minoxidil Sulphate Journal of Microencapsulation · 2011
    6. Selective Follicular Targeting by Modification of the Particle Sizes Journal of Controlled Release · 2011
    7. Targeting to the Hair Follicles: Current Status and Potential Journal of dermatological science · 2010
    8. Differential Stripping: Determination of the Amount of Topically Applied Substances Penetrated into the Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005
    9. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    10. Allergic Contact Dermatitis to Topical Minoxidil Solution: Etiology and Treatment Journal of The American Academy of Dermatology · 2002
    11. Minoxidil Sulfate Is the Active Metabolite That Stimulates Hair Follicles Journal of Investigative Dermatology · 1990