Chitosan Microparticles for Sustaining the Topical Delivery of Minoxidil Sulphate

    August 2011 in “ Journal of Microencapsulation
    Tais Gratieri, Patrícia Sper Simão, Luís Alexandre Pedro de Freitas, Norberto Peporine Lopes
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    TLDR Chitosan microparticles improve minoxidil sulphate delivery, potentially reducing daily applications.
    This document describes a study on the use of chitosan microparticles to sustain the topical delivery of minoxidil sulphate (MXS) for the treatment of alopecia. The microparticles were prepared by spray drying and characterized for yield, efficiency of encapsulation, size distribution, morphology, and release rate of MXS. The study found that chitosan microparticles could be a promising drug delivery system for sustained topical delivery of MXS to hair follicles, potentially decreasing the number of applications needed throughout the day.
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