Dutasteride Nanocapsules for Hair Follicle Targeting: Effect of Chitosan-Coating and Physical Stimulus

February 2020 in “ International Journal of Biological Macromolecules ”

Camila Y. Ushirobira, Luana Alves Freitas Afiune, Maíra N. Pereira, Angel Concheiro, Tais Gratieri

dutasteride nanocapsules chitosan-coating physical stimulus hair follicle targeting controlled drug release follicular shaft follicular casts Avodart

TLDR Chitosan-coated dutasteride nanocapsules improve hair treatment, and physical stimulation boosts effectiveness.

The study investigated the use of dutasteride nanocapsules for targeted hair follicle treatment. Chitosan-coating was found to enhance drug delivery and provide controlled drug release, while physical stimulus significantly improved nanoparticles accumulation into the follicular shaft. The study demonstrated that dutasteride nanocapsules can target the follicular casts, and a simple physical stimulation can enhance the drug amount accumulated.

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Research cited in this study

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research Dutasteride Nanocapsules for Hair Follicle Targeting: Effect of Chitosan-Coating and Physical Stimulus

26 citations, February 2020 in “International Journal of Biological Macromolecules”

Chitosan-coated dutasteride nanocapsules improve hair treatment, and physical stimulation boosts effectiveness.

Dutasteride Nanocapsules for Hair Follicle Targeting: Effect of Chitosan-Coating and Physical Stimulus

Research cited in this study

research The Efficacy and Safety of Dutasteride Compared with Finasteride in Treating Men with Androgenetic Alopecia: A Systematic Review and Meta-Analysis

research Prospective Randomized Study of Sexual Function in Men Taking Dutasteride for the Treatment of Androgenetic Alopecia

research Preparation and Characterization of Dutasteride-Loaded Nanostructured Lipid Carriers Coated with Stearic Acid-Chitosan Oligomer for Topical Delivery

research Dutasteride in Androgenetic Alopecia: An Update

research Solid Effervescent Formulations as a New Approach for Topical Minoxidil Delivery

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