Trichotillomania: Differences From OCD and Treatment Approaches

    September 2016 in “ American Journal of Psychiatry
    Jon E. Grant, Samuel R. Chamberlain
    TLDR Trichotillomania is different from OCD and is best treated with habit reversal therapy and specific medications.
    The document discussed trichotillomania, a psychiatric condition characterized by compulsive hair pulling, leading to hair loss and functional impairment. It highlighted the case of "Ms. G," a 22-year-old woman who reduced her hair-pulling behavior through habit reversal therapy and N-acetylcysteine treatment. Trichotillomania was more prevalent in females and often began in adolescence. The condition was associated with psychosocial dysfunction, low self-esteem, and social anxiety. Prevalence studies showed varying rates, with higher estimates using newer DSM criteria. Trichotillomania was often comorbid with disorders like depression and anxiety, and it was frequently misdiagnosed as OCD. The document also explored the possible pathophysiology, including genetic components and neuroimaging findings, though data were limited. The document reviewed various studies on trichotillomania, highlighting brain structure differences, psychological factors, and treatment options. Studies showed that individuals with trichotillomania had differences in gray and white matter compared to healthy subjects, suggesting neurocircuitry disorganization. Psychological theories proposed that hair pulling might regulate emotional states, with habit reversal therapy being the most promising treatment. Pharmacotherapy options like N-acetylcysteine showed potential benefits, though no universally accepted first-line treatment existed. The document emphasized the importance of thorough medical and psychiatric assessments, especially for those engaging in trichophagia, due to potential severe complications.
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