Preparation and Evaluation of Minoxidil Foamable Emu Oil Emulsion

    February 2015 in “ PubMed ”
    Shatalebi, Y Rafiei
    TLDR The emu oil emulsion with minoxidil was better at promoting hair growth than the commercial product.
    In 2015, a study was conducted to develop a foamable emulsion of minoxidil and emu oil, aiming to enhance minoxidil's permeation into the skin and increase hair growth. Seventeen formulations were prepared, with the most stable one, F17, selected for evaluation. This formulation showed good pharmaceutical characteristics and a controlled drug release over 6 hours. It was stable at 8°C and 25°C for a month, but showed slight phase separation at 40°C. It did not cause skin irritation in rats. The hair growth activity evaluation showed a significant increase in the number of hair follicles in the anagen phase in the group receiving the F17 formulation compared to the control group. By the 30th day, the F17 formulation showed the maximum number of anagen hair follicles (96%) compared to the control group and other formulations. The study concluded that the F17 formulation significantly improved hair growth and was well compatible with skin, causing no sensitivity reaction in the animal model used. Further studies in humans were recommended to confirm its suitability and safety profile.
    Discuss this study in the Community →

    Research cited in this study

    6 / 6 results

    Related Community Posts Join

    6 / 1000+ results

      community Injecting stomach fat into the scalp could cure baldness in just six months

      in Update  114 upvotes 6 years ago
      A potential treatment for hair loss that involves injecting fat into the scalp; the role of testosterone and estrogen in thinning fat tissue under the skin; research on using lard to treat androgenic alopecia, as well as PRP + ACELL/amniotic stem cell treatments; and ongoing clinical trials by doctors involved in the study.

      community Rosemary oil, peppermint oil, mucuna pruriens - two weeks in

      in Treatment  84 upvotes 1 year ago
      A user who is trying alternative treatments, such as mucuna pruriens dissolved in water/alcohol and a blend of jojoba oil, rosemary oil, and peppermint oil, for hair loss. Other users have shared anecdotal evidence, discussed the potential effectiveness of certain treatments, and questioned the time sensitivity of experimenting with new treatments.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  138 upvotes 9 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

      community Hair Regrowth with Novel Hemp Extract - anyone seen this??

      in Research/Science  18 upvotes 3 months ago
      A user discusses a novel hemp extract for hair regrowth, which showed superior results to finasteride and minoxidil. The formula includes CBD, CBDV, THCV, delta 9 THC, cannabigerol, and cannabinol, combined with menthol, peppermint oil, ethanol, Emu oil, HFA 134A propellant, and dimethicone.

    Related Research

    1 / 1 results