Design of Finasteride-Loaded Nanoparticles for Potential Treatment of Alopecia

January 2017 in “ Skin Pharmacology and Physiology ”

Luís A. C. Roque, Inês S Dias, Nuno Cruz, Ana Cristina Silva Rebelo, Amílcar Roberto, Maria José Calhorda, Catarina Pinto Reis

finasteride nanoparticles PLGA nanoparticles topical formulations lotion shampoo solution alopecia Propecia

TLDR Finasteride-loaded nanoparticles may help treat alopecia.

The study aimed to develop a potential treatment for alopecia using finasteride-loaded nanoparticles. The study produced PLGA nanoparticles loaded with finasteride and incorporated them into three different types of topical formulations: lotion, shampoo, and solution. The study found that the developed finasteride-loaded nanoparticles have potential for the treatment of alopecia. The study suggests that finasteride-loaded nanoparticles have potential as a topical treatment for alopecia.

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Research cited in this study

6 / 6 results

research Design and In Vitro Evaluation of Finasteride-Loaded Liquid Crystalline Nanoparticles for Topical Delivery

58 citations, December 2012 in “Aaps Pharmscitech”

LCN may improve finasteride delivery for hair loss treatment.

research Evaluation of Efficacy and Safety of Finasteride 1 mg in 3177 Japanese Men with Androgenetic Alopecia

41 citations, October 2011 in “Journal of Dermatology”

Finasteride 1 mg effectively and safely increases hair growth in Japanese men with hair loss.

research Preparation of Novel Polymeric Microspheres for Controlled Release of Finasteride

37 citations, September 2007 in “International Journal of Pharmaceutics”

PPCM microspheres allow controlled finasteride release over 24 hours.

research Development of Liposomal Systems of Finasteride for Topical Applications: Design, Characterization, and In Vitro Evaluation

56 citations, January 2007 in “Pharmaceutical Development and Technology”

Liposomes improve finasteride delivery for hair loss treatment, making it a promising option for topical use.

research Finasteride in the Treatment of Androgenetic Alopecia

62 citations, April 2004 in “Expert Opinion on Pharmacotherapy”

Finasteride effectively treats male pattern baldness, improving hair growth and density.

research The Value of Hair Cosmetics and Pharmaceuticals

59 citations, January 2001 in “Dermatology”

Hair care products are important for appearance and self-esteem, and their benefits and risks should be accurately communicated by experts.

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research Finasteride for Androgenetic Alopecia

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Finasteride increases hair count in men with hair loss, but the effect isn't permanent and hair loss returns if treatment stops.

Design of Finasteride-Loaded Nanoparticles for Potential Treatment of Alopecia

Research cited in this study

research Design and In Vitro Evaluation of Finasteride-Loaded Liquid Crystalline Nanoparticles for Topical Delivery

research Evaluation of Efficacy and Safety of Finasteride 1 mg in 3177 Japanese Men with Androgenetic Alopecia

research Preparation of Novel Polymeric Microspheres for Controlled Release of Finasteride

research Development of Liposomal Systems of Finasteride for Topical Applications: Design, Characterization, and In Vitro Evaluation

research Finasteride in the Treatment of Androgenetic Alopecia

research The Value of Hair Cosmetics and Pharmaceuticals

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