Minoxidil Therapy in Refractory Hypertension: Analysis of 155 Patients

January 1978 in “ Nephron ”

Gerald T. Keusch, Peter Weidmann, Vito M. Campese, D. M. Lee, A. Upham, Shaul G. Massry

TLDR Minoxidil lowers blood pressure effectively but may cause side effects.

The study analyzed the use of Minoxidil as a treatment for refractory hypertension in 155 patients. Minoxidil was found to be effective in lowering blood pressure, with a maximum effect occurring within the first 2 weeks of treatment. However, blood pressure tended to rise thereafter despite increasing doses of Minoxidil. The study also noted that Minoxidil was well-tolerated in most patients, but some experienced intolerable side effects and one patient died from cardiac arrest after 2 weeks of treatment. Overall, the study suggests that Minoxidil may be a viable alternative medical therapy for patients with refractory hypertension.

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$Minoxidil in Refractory Hypertension$

research Minoxidil in Refractory Hypertension

17 citations, April 1975 in “The Journal of Pediatrics”

Minoxidil effectively controls severe high blood pressure in children with few side effects.