Minoxidil Therapy in Refractory Hypertension: Analysis of 155 Patients
January 1978
in “
Nephron
”
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Studysummary Minoxidil lowers blood pressure effectively but may cause side effects. Our plain-language summary of this paper — not a Tressless recommendation.
The study analyzed the use of Minoxidil as a treatment for refractory hypertension in 155 patients. Minoxidil was found to be effective in lowering blood pressure, with a maximum effect occurring within the first 2 weeks of treatment. However, blood pressure tended to rise thereafter despite increasing doses of Minoxidil. The study also noted that Minoxidil was well-tolerated in most patients, but some experienced intolerable side effects and one patient died from cardiac arrest after 2 weeks of treatment. Overall, the study suggests that Minoxidil may be a viable alternative medical therapy for patients with refractory hypertension.
