Androgenetic Alopecia: An Update

    July 2023 in “ JAAD International ”
    Sylvia Ntombifuthi. Ntshingila, Ogheneochuko. Oputu, Afolake Arowolo, Nonhlanhla P. Khumalo
    Studysummary This study describes androgenetic alopecia as a common non-scarring hair loss condition primarily influenced by genetic factors and androgen sensitivity, notably impacting psychosocial well-being, especially in females and younger males seeking treatment.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 66

    1. Comparison of Oral Minoxidil, Finasteride, and Dutasteride for Treating Androgenetic Alopecia Journal of Dermatological Treatment · 2022
    2. All That a Dermatotrichologist Needs to Know About Hair Camouflage: A Comprehensive Review International Journal of Trichology · 2022
    3. Exosome Therapy in Hair Regeneration: A Literature Review of the Evidence, Challenges, and Future Opportunities Journal of cosmetic dermatology · 2022
    4. Topical Finasteride for Male and Female Pattern Hair Loss: Is It a Safe and Effective Alternative? Journal of Cosmetic Dermatology · 2022
    5. Advances in Hair Restoration: Wnt/Beta-Catenin Pathway and Stem Cell-Based Therapies Current Otorhinolaryngology Reports · 2021
    6. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    7. A Systematic Review and Meta-Analysis of Randomized Controlled Trials of United States Food and Drug Administration-Approved, Home-Use, Low-Level Light/Laser Therapy Devices for Pattern Hair Loss: Device Design and Technology PubMed · 2021
    8. Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target Journal of Medicinal Chemistry · 2021
    9. An Appraisal of Laboratory Models of Androgenetic Alopecia: A Systematic Review Skin health and disease · 2021
    10. Role of Low-Level Light Therapy in Androgenetic Alopecia Journal of Cutaneous and Aesthetic Surgery · 2021
    11. Structure of Human Steroid 5α-Reductase 2 with the Anti-Androgen Drug Finasteride Nature Communications · 2020
    12. Microneedling in Androgenetic Alopecia: Comparing Two Different Depths of Microneedles Journal of Cosmetic Dermatology · 2020
    13. Microneedling: A Novel Therapeutic Approach for Androgenetic Alopecia, A Review of Literature Dermatologic Therapy · 2020
    14. The Effectiveness of Combination Therapies for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Dermatologic Therapy · 2020
    15. The Role of Mutations on Gene AR in Androgenetic Alopecia Syndrome International journal of molecular biology · 2020
    16. Current Advances in Stem Cell-Based Therapies for Hair Regeneration European Journal of Pharmacology · 2020
    17. Clascoterone as a Novel Treatment for Androgenetic Alopecia Clinical and Experimental Dermatology · 2020
    18. Platelet-Rich Plasma as a Therapy for Androgenic Alopecia: A Systematic Review and Meta-Analysis Journal of Dermatological Treatment · 2020
    19. A Study on the Efficacy of Microneedling with Minoxidil Solution Versus Microneedling with Hair Multivitamin Solution for the Treatment of Androgenetic Alopecia International journal of dermatology and clinical research · 2020
    20. Finasteride and Its Potential for the Treatment of Female Pattern Hair Loss: Evidence to Date Drug Design Development and Therapy · 2020
    21. Examining the Safety and Efficacy of Low-Level Laser Therapy for Male and Female Pattern Hair Loss: A Review of the Literature Skin appendage disorders · 2020
    22. Exosomes: A New Effective Non-Surgical Therapy for Androgenetic Alopecia? Skinmed · 2020
    23. Herbal Preparations for the Treatment of Hair Loss Archives of Dermatological Research · 2019
    24. Pattern Hair Loss: Assessment of Inflammation and Fibrosis on Histologic Sections Journal of The American Academy of Dermatology · 2019
    25. Exosome for Hair Regeneration: From Bench to Bedside Journal of the American Academy of Dermatology · 2019
    26. Physiopathology and Current Treatments of Androgenetic Alopecia: Going Beyond Androgens and Anti-Androgens Dermatologic Therapy · 2019
    27. An Overview of Herbal Alternatives in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2019
    28. Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia Dermatologic Surgery · 2019
    29. Cortexolone 17α-Propionate (Clascoterone) Is an Androgen Receptor Antagonist in Dermal Papilla Cells In Vitro PubMed · 2019
    30. The Efficacy and Safety of Dutasteride Compared with Finasteride in Treating Men with Androgenetic Alopecia: A Systematic Review and Meta-Analysis Clinical Interventions in Aging · 2019
    31. Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors Assay and Drug Development Technologies · 2018
    32. Randomized Controlled Trial on a PRP-Like Cosmetic with Biomimetic Peptides for the Treatment of Alopecia Areata Journal of Dermatological Treatment · 2018
    33. Platelet-Rich Plasma for Androgenetic Alopecia: A Review of the Literature and Proposed Treatment Protocol International Journal of Women's Dermatology · 2018
    34. Minoxidil in the Treatment of Androgenetic Alopecia Dermatologic Therapy · 2018
    35. Efficacy of Non-Surgical Treatments for Androgenetic Alopecia: A Systematic Review and Network Meta-Analysis Journal of The European Academy of Dermatology and Venereology · 2018
    36. A Systematic Review of Topical Finasteride in the Treatment of Androgenetic Alopecia in Men and Women PubMed · 2018
    37. Minoxidil Promotes Hair Growth Through Stimulation of Growth Factor Release from Adipose-Derived Stem Cells International Journal of Molecular Sciences · 2018
    38. Minoxidil Downregulates Interleukin-1 Alpha Gene Expression in HaCaT Cells International Journal of Trichology · 2018
    39. Genetic and Molecular Aspects of Androgenetic Alopecia Indian Journal of Dermatology, Venereology and Leprology · 2018
    40. Meta-Analysis on Evidence of Platelet-Rich Plasma for Androgenetic Alopecia International Journal of Trichology · 2018
    41. Adverse Effects with Finasteride 5 mg/Day for Patterned Hair Loss in Premenopausal Women International Journal of Trichology · 2018
    42. 5α-Reductase Isozymes and Aromatase mRNA Levels in Plucked Hair from Young Women with Female Pattern Hair Loss Archives of Dermatological Research · 2017
    43. A Novel Multi-Targeting Approach to Treating Hair Loss Using Standardized Nutraceuticals PubMed · 2017
    44. Hair Loss: Common Causes and Treatment PubMed · 2017
    45. The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2017
    46. Dutasteride in Androgenetic Alopecia: An Update Current Clinical Pharmacology · 2017
    47. Hair Camouflage: A Comprehensive Review International Journal of Women's Dermatology · 2017
    48. Standardization of SMP Procedure and Its Impact on Outcome Journal of Cutaneous and Aesthetic Surgery · 2017
    49. Low-Level Laser Therapy as a Treatment for Androgenetic Alopecia Lasers in Surgery and Medicine · 2016
    50. Differential Expression Between Human Dermal Papilla Cells from Balding and Non-Balding Scalps Reveals New Candidate Genes for Androgenetic Alopecia Journal of Investigative Dermatology · 2016
    51. The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial Stem Cells Translational Medicine · 2015
    52. The Inhibitory Effect of Scutellaria Baicalensis Extract and Its Active Compound, Baicalin, on the Translocation of the Androgen Receptor with Implications for Preventing Androgenetic Alopecia Planta Medica · 2014
    53. Androgenetic Alopecia: Overview, Epidemiology, Pathophysiology, and Treatment Journal of the Egyptian Women's Dermatologic Society (Print) · 2013
    54. Female Pattern Alopecia: Current Perspectives International Journal of Women's Health · 2013
    55. A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study International Journal of Trichology · 2013
    56. The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases Advances in Urology · 2011
    57. Androgen Receptor Gene Polymorphisms and Risk for Androgenetic Alopecia: A Meta-Analysis Clinical and Experimental Dermatology · 2011
    58. Gene-Wide Association Study Between the Aromatase Gene (CYP19A1) and Female Pattern Hair Loss British Journal of Dermatology · 2009
    59. Kenogen in Female Androgenetic Alopecia Dermatology · 2004
    60. Androgens and Alopecia Molecular and Cellular Endocrinology · 2002
    61. The Prevalence and Types of Androgenetic Alopecia in Korean Men and Women British Journal of Dermatology · 2001
    62. Polymorphism of the Androgen Receptor Gene Is Associated with Male Pattern Baldness Journal of Investigative Dermatology · 2001
    63. Antiandrogen Therapy in Dermatology International Journal of Dermatology · 1996
    64. Aetiology and Pathophysiology of Hair Loss Dermatology · 1987
    65. Hair Camouflage: A Comprehensive Review International Journal of Women's Dermatology · 1982
    66. Classification of the Types of Androgenetic Alopecia (Common Baldness) Occurring in the Female Sex British Journal of Dermatology · 1977

    Related research 9

    1. Pharmacological Therapeutics in Androgenetic Alopecia Journal of The Korean Medical Association · 2020
    2. Efficacy of Non-Surgical Treatments for Androgenetic Alopecia: A Systematic Review and Network Meta-Analysis Journal of The European Academy of Dermatology and Venereology · 2018
    3. Combined Treatment with Oral Finasteride and Topical Minoxidil in Male Androgenetic Alopecia: A Randomized and Comparative Study in Chinese Patients Dermatologic Therapy · 2015
    4. A New Topical Formulation of Minoxidil and Finasteride Improves Hair Growth in Men with Androgenetic Alopecia Journal of clinical & experimental dermatology research · 2015
    5. Finasteride in the Treatment of Female Androgenic Alopecia PharmaTutor · 2014
    6. Daily Finasteride Boosts Hair Growth in Men Dermatology Times E-News · 2012
    7. Use of Finasteride in the Treatment of Men With Androgenetic Alopecia Journal of Investigative Dermatology Symposium Proceedings · 2003
    8. Advances in the Treatment of Male Androgenetic Alopecia: A Brief Review of Finasteride Studies PubMed · 2001
    9. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998