Gene-Knockout Mice With Abnormal Epidermal and Hair Follicular Development

    November 1998 in “ Journal of dermatological science
    Kiyofumi Yamanishi
    TLDR Knocking out certain genes in mice helps understand skin and hair growth problems.
    The study titled "Gene-knockout mice with abnormal epidermal and hair follicular development" from November 1, 1998, investigated the effects of specific gene knockouts on the development of the epidermis and hair follicles in mice. The researchers found that the absence of certain genes led to significant abnormalities in both the skin and hair follicle structures. These findings suggested that these genes played crucial roles in normal skin and hair development. The study provided insights into the genetic mechanisms underlying hair growth and skin formation, which could have implications for understanding and treating conditions like alopecia.
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