Finasteride Is the Main Inhibitor of 5α-Reductase Activity in Microdissected Dermal Papillae of Human Hair Follicles
February 1999
in “
Archives of Dermatological Research
”
![Image of study](/images/research/104cf6c2-d495-4bfd-b9fe-dc77d7c18662/medium/2216.jpg)
TLDR Finasteride potentially treats hair loss by reducing DHT production.
The study found that finasteride is the main inhibitor of 5α-reductase activity in microdissected dermal papillae of human hair follicles, indicating its potential effectiveness in treating androgenetic alopecia. The study involved a small number of human subjects and suggests that finasteride may be a useful treatment for hair loss by reducing DHT production.