Finasteride Is the Main Inhibitor of 5α-Reductase Activity in Microdissected Dermal Papillae of Human Hair Follicles

    February 1999 in “ Archives of Dermatological Research
    Rolf Hoffmann, Rudolf Happle
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    TLDR Finasteride potentially treats hair loss by reducing DHT production.
    The study found that finasteride is the main inhibitor of 5α-reductase activity in microdissected dermal papillae of human hair follicles, indicating its potential effectiveness in treating androgenetic alopecia. The study involved a small number of human subjects and suggests that finasteride may be a useful treatment for hair loss by reducing DHT production.
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