Fructose-1,6-Bisphosphate Aldolase A Levels Decrease in Hair Keratinocytes During Androgenetic Alopecia

November 2013 in “ International Journal of Dermatology ”

Takumi Tochio, Hiroshi Tanaka, Satoru Nakata, Hiroshi Hosoya

fructose-1,6-bisphosphate aldolase A ALDOA hair keratinocytes androgenetic alopecia AGA vellus hairs hair shaft elongation

TLDR ALDOA levels drop in hair cells during hair loss.

Levels of fructose-1,6-bisphosphate aldolase A (ALDOA) decrease in hair keratinocytes during androgenetic alopecia (AGA). ALDOA is involved in the morphological alteration of hair keratinocytes during elongation of hair shafts, and a decrease in ALDOA in vellus hairs might be involved in reduced hair shaft elongation. However, the mechanism behind the association of ALDOA with the progression of AGA remains to be fully clarified. Further studies are needed to elucidate the involvement of ALDOA in AGA.

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research Fructose-1,6-Bisphosphate Aldolase A Levels Decrease in Hair Keratinocytes During Androgenetic Alopecia

2 citations, November 2013 in “International Journal of Dermatology”

ALDOA levels drop in hair cells during hair loss.