The Stumptailed Macaque as a Model for Androgenetic Alopecia: Effects of Topical Minoxidil Analyzed by Use of the Folliculogram

October 1988 in “ Clinics in Dermatology ”

Pamela A. Brigham, Adrienne Cappas, Hideo Uno

androgenetic alopecia minoxidil folliculogram hair growth follicles resting follicles Rogaine

TLDR The study used monkeys to test a hair loss treatment called minoxidil, which showed positive results.

This study used stumptailed macaques as a model for androgenetic alopecia and analyzed the effects of topical minoxidil on hair growth using the folliculogram method. The results showed that minoxidil increased the number of hair growth follicles and decreased the number of resting follicles, suggesting it may be an effective treatment for androgenetic alopecia in humans. The study also found that minoxidil treatment resulted in thicker and darker hair growth in bald areas without any negative effects on the skin.

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Research cited in this study

6 / 6 results

research The Metabolism and Control Mechanism of Human Hair Follicles

22 citations, April 2015 in “Current problems in dermatology”

Human hair follicles have a unique metabolism that changes between growth stages and may contribute to baldness.

research Androgenetic Alopecia Treated With Topical Minoxidil

32 citations, March 1987 in “Journal of The American Academy of Dermatology”

Using minoxidil on balding men's scalps can increase hair growth, according to a 12-month study.

research Long-Term Follow-Up of Men with Male Pattern Baldness Treated with Topical Minoxidil

51 citations, March 1987 in “Journal of The American Academy of Dermatology”

Minoxidil keeps most hair growth from first year and twice-daily use is better with few side effects.

research Action of Topical Minoxidil in the Bald Stump-Tailed Macaque

78 citations, March 1987 in “Journal of The American Academy of Dermatology”

Minoxidil promotes hair growth but stops working when discontinued.

research The Stumptailed Macaque as a Model for Baldness: Effects of Minoxidil

18 citations, April 1986 in “International Journal of Cosmetic Science”

Minoxidil promotes hair regrowth in early baldness stages and prevents baldness in non-bald scalps.

research Cyclic Dynamics of Hair Follicles and the Effect of Minoxidil on the Bald Scalps of Stumptailed Macaques

54 citations, June 1985 in “American Journal of Dermatopathology”

Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.

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6 / 1000+ results

community can someone please tell me its going to get better? im bawling my eyes out

in Female 67 upvotes 2 years ago

A 16-year-old girl is experiencing hair loss, which has worsened despite using minoxidil and multivitamins. Suggestions include broader hormone testing and considering other treatments like spironolactone if the hair loss is due to androgenic alopecia.

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community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens.

in Research/Science 1 upvotes 1 week ago

A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.

community Evidenced Based Meta-Analyses and Systemic Reviews of Androgenic Alopecia and Treatments

in Research/Science 14 upvotes 4 years ago

Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.

community Comparison of options: topical vs medication

in Female 1 upvotes 6 months ago

A user diagnosed with AGA is seeking advice on hair loss treatments, comparing topical Minoxidil, Spironolactone, and Finasteride to oral medications and natural methods like dermastamping, PRP, and LED light. They are concerned about side effects and effectiveness, especially given their existing fatigue.

community Low-dose daily aspirin reduces topical minoxidil efficacy in androgenetic alopecia patients.

in Minoxidil 6 upvotes 5 years ago

Low-dose daily aspirin reduces the effectiveness of topical minoxidil in treating androgenetic alopecia. Aspirin inhibits sulfotransferase enzymes, which are necessary for minoxidil to work.

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A woman had an unusual allergic reaction to a hair loss treatment, which cleared up after stopping the treatment and using a different medication.

research Effectivity of Minoxidil as a Treatment for Alopecia Areata

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Minoxidil can effectively treat patchy hair loss by stimulating hair growth.

research Alopecia Areata Treated With Topical Minoxidil

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Topical minoxidil can help hair regrowth in alopecia areata patients, but maintaining the growth after stopping treatment is inconsistent.