The Stumptailed Macaque as a Model for Baldness: Effects of Minoxidil

April 1986 in “ International Journal of Cosmetic Science ”

Hideo Uno

minoxidil male pattern baldness terminal hairs topical application epidermal keratinocytes sebaceous glands dermal components Rogaine

TLDR Minoxidil promotes hair regrowth in early baldness stages and prevents baldness in non-bald scalps.

The study investigated the effects of minoxidil on baldness in stumptailed macaques, which is biologically similar to male pattern baldness in humans. The researchers found that topical application of minoxidil induced regrowth of terminal hairs in bald scalps of macaques, with greater results in the early stages of baldness in adolescent and young adults. Minoxidil also prevented the development of baldness when applied on non-bald scalps of peri-adolescent animals. The study concluded that the stumptailed macaque is a useful animal model for the study of human male pattern baldness, and minoxidil has no influence on epidermal keratinocytes, sebaceous glands, and other dermal components.

View this study on doi.org →

Discuss this study in the Community →

Research cited in this study

1 / 1 results

research Cyclic Dynamics of Hair Follicles and the Effect of Minoxidil on the Bald Scalps of Stumptailed Macaques

54 citations, June 1985 in “American Journal of Dermatopathology”

Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.

Related Community Posts Join

6 / 1000+ results

community COMPLETE OVERVIEW of the Treatment of androgenetic alopecia in men

26 upvotes 10 years ago

Male androgenetic alopecia is commonly treated with topical minoxidil and oral finasteride, both requiring continuous use. Other options include hair restoration surgery, dutasteride, light therapy, and camouflaging agents.

community Day 1 vs Day 168 (today) of defeating the norwood reaper

in Progress Pictures 1510 upvotes 3 months ago

The user achieved significant hair regrowth using topical 5% minoxidil and oral 1mg finasteride daily, especially around the temples. They experienced minimal side effects, with initial difficulty maintaining erections that resolved after a few weeks.

community Been on Propecia since 1997, recently switched to Topical Finasteride.. follow for updates, or to ask any questions about 23 years on Propecia.

in Finasteride/Dutasteride 101 upvotes 3 years ago

User spent 23 years on Finasteride with side effects like weight gain and reduced libido. Switched to topical Finasteride, side effects reduced and waiting for results.

community 32, Southeast Asian, 1 y 3 m Finasteride, Dutasteride, Minoxidil, Microneedling – Former hair system user. Quick description of routine in comments.

in Progress Pictures 324 upvotes 2 years ago

A user named "bmbshell" who was dealing with hair loss and initially tried to fix it with a hair system before deciding to try finasteride, dutasteride, minoxidil, microneedling, and biotin supplements. They documented their progress over the past 1 year and 3 months, showing how effective these treatments were in regrowing their hair.

community Hair Loss Drugs Ranked in Order of Efficacy

in Research/Science 67 upvotes 1 year ago

Dutasteride is likely the most effective treatment for male pattern baldness, followed by finasteride and minoxidil in various forms and dosages. Users discuss personal experiences, dosages, and potential side effects, with some considering combining treatments for better results.

community Dermarolling and Min are proven to be the absolute best way to get new hairs, there is no comparison.

in Microneedling 127 upvotes 2 years ago

Fin and minoxidil, in combination with dermarolling, as an effective path for hair growth. The post also provides advice about needle depth and frequency, as well as other treatments (foam and oral) which may be beneficial.

Related Research

1 / 1 results

research The Effect of Topical RU58841 (Androgen Receptor Blocker) Combined with Minoxidil on Hair Growth in Macaque Androgenetic Alopecia

March 1998 in “Journal of Dermatological Science”

Combining RU58841 and minoxidil significantly increases hair growth.