The Effect of Topical RU58841 (Androgen Receptor Blocker) Combined with Minoxidil on Hair Growth in Macaque Androgenetic Alopecia

    March 1998 in “ Journal of Dermatological Science ”
    Koreyoshi Imamura, A. Bonfils, A. Diani, Hitoshi Uno
    Image of study
    TLDR Combining RU58841 and minoxidil significantly increases hair growth.
    This collection of documents covers a range of topics, but only a few are related to hair loss, alopecia, and hair growth. The studies that are relevant investigate the effect of combining topical RU58841, an androgen receptor blocker, with minoxidil on hair growth in macaque androgenetic alopecia. The results show that the combination treatment leads to a significant increase in hair growth compared to using either treatment alone. The studies suggest that combining these two treatments may be a promising approach for treating androgenetic alopecia in humans. One study involved six macaques and lasted for 20 weeks, while another involved three groups of monkeys, each receiving a different treatment. Long-term observation is needed to determine the synergistic effects of the combined treatment on follicular growth.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Homemade topical spironolactone

      in Research/Science  26 upvotes 2 years ago
      The potential effectiveness of homemade topical spironolactone in treating hair loss, with studies suggesting it is more effective than finasteride and even minoxidil when used as monotherapy. The conversation also mentions that other anti-androgens are being developed which may soon hit the market.

      community #BIG4 plus vitamins and biotin/ 6 Months results/ 26 years old/ Extreme MPB

      in Progress Pictures  237 upvotes 2 years ago
      A 26-year-old with extreme male pattern baldness saw hair regrowth after 6 months using Minoxidil, Finasteride, microneedling, Nizoral, a vitamin complex, biotin, and a shampoo with baicapil. Continuation of treatment is necessary to maintain results; stopping may lead to hair loss, making a hair transplant a potential future option.

      community Why is it that low testosterone causes hair loss as well? How can I be balding?

      in Chat  158 upvotes 6 months ago
      The conversation discusses the confusion over low testosterone potentially causing hair loss, with users sharing personal experiences and knowledge about hair loss treatments like Finasteride. Some users suggest that hair follicle sensitivity to DHT, not testosterone levels, is the key factor in balding, and others discuss the side effects of hair loss medications.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  136 upvotes 6 months ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

    Related Research

    11 / 11 results