15 months total on Dut/Min/RU and microneedling 1mm every other week
    9/1/2024

    From the encyclopedia
    Dutasteride →

    5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride

    Minoxidil →

    Vasodilator used on the scalp and, at low doses, as a tablet

    RU58841 →

    Experimental topical anti-androgen sold as a research chemical

    At a glance
    In this treatment experience post, the primary subjects mentioned are
    💊 Dutasteride (oral) 0.5mg daily 15 months
    💊 Minoxidil (oral) 5mg daily 15 months
    💧 Minoxidil (topical) twice a day 15 months
    💧 RU58841 (topical) 70mg daily 15 months
    💧 Ketoconazole (topical) twice a week 15 months
    💧 Microneedling (topical) 1mm every other week 15 months
    the tone is 😀 positive with significant improvement results.

    Other terms

    The user reported significant hair improvement over 15 months using dutasteride, minoxidil (oral and topical), RU58841, ketoconazole, and microneedling. They are considering a hair transplant in 4-6 months.
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      research Experimental and early investigational drugs for androgenetic alopecia

      11 citations , July 2017 in “Expert Opinion on Investigational Drugs”
      This review discusses current and emerging therapeutic strategies for androgenetic alopecia, noting limited evidence but suggesting areas such as prostaglandin analogs, PRP, and progenitor cell therapies as promising future directions.

      research Androgenetic Alopecia: An Update on Pathogenesis and Pharmacological Treatment

      August 2025 in “Drug Design Development and Therapy”
      This review article examines current drugs for androgenetic alopecia, focusing on their mechanisms and clinical efficacy, noting that while finasteride and minoxidil are commonly approved treatments, new drugs targeting different pathogenic pathways have emerged, offering a broader understanding and reference for AGA treatment options.

      research Antiandrogens and Androgen Inhibitors

      November 2020 in “Elsevier eBooks”
      This source outlines various antiandrogen and androgen inhibitor drugs used to treat cutaneous disorders of hyperandrogenism, detailing their mechanisms, uses, dosages, and side effects, with emphasis on spironolactone, finasteride, dutasteride, and oral contraceptives.

      research Hair loss and herbs for treatment

      39 citations , September 2013 in “Journal of Cosmetic Dermatology”
      This review summarizes causes and treatments of androgenetic alopecia with a focus on herbs as potential alternatives, but reports no new results and suggests more research is needed to validate these options.