Hair Growth Promoting Effect of White Wax and Policosanol from White Wax on the Mouse Model of Testosterone-Induced Hair Loss

    February 2017 in “ Biomedicine & Pharmacotherapy ”
    Zhan-di Wang, Ying Feng, Liang Ma … Xiaoming Chen
    Studysummary This study found that white wax and its extract may promote hair growth in a mouse model of androgenetic alopecia by inhibiting 5α-reductase activity and increasing cell proliferation, with efficacy surpassing finasteride.
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    Research cited in this study 9

    1. Guidelines on the Use of Finasteride in Androgenetic Alopecia Indian Journal of Dermatology, Venereology and Leprology · 2016
    2. Assessment of the Usefulness of Dihydrotestosterone in the Diagnostics of Patients with Androgenetic Alopecia Postepy Dermatologii I Alergologii · 2014
    3. Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences Between Sox2-Positive and Sox2-Negative Cells In Vitro and In Vivo Journal of Investigative Dermatology · 2011
    4. Effects of Ginseng Rhizome and Ginsenoside Ro on Testosterone 5α-Reductase and Hair Regrowth in Testosterone-Treated Mice Phytotherapy Research · 2011
    5. Effect of Citrullus Colocynthis Schrad Fruits on Testosterone-Induced Alopecia Natural Product Research · 2009
    6. Transfollicular Drug Delivery: Is It a Reality? International journal of pharmaceutics · 2005
    7. Finasteride in the Treatment of Androgenetic Alopecia Expert Opinion on Pharmacotherapy · 2004
    8. Effect of Minoxidil on Proliferation and Apoptosis in Dermal Papilla Cells of Human Hair Follicle Journal of Dermatological Science · 2004
    9. A Case of Acute Myocardial Infarction Associated with Topical Use of Minoxidil for Treatment of Baldness Japanese Heart Journal · 2000