TLDR A man developed heart problems after using a baldness treatment for 4 months, suggesting that people with heart issues should avoid this treatment.
In 1999, a 45-year-old Japanese man with a history of paroxysmal atrial fibrillation developed acute myocardial infarction (MI) after using 1% topical minoxidil (RiUP®) for baldness treatment for 4 months. The patient had no history of hypertension, obesity, diabetes mellitus, or family history of coronary artery disease. Coronary angiography revealed severe stenosis at the proximal portion of the left anterior descending coronary artery. The report suggested that while it may be difficult to directly link topical minoxidil use to myocardial ischemia, increased awareness of its potential toxicity was necessary. It was recommended that patients with cardiovascular disorders should be excluded from the therapy.
5 citations
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October 1993 in “International Journal of Dermatology” Topical minoxidil is effective and safe for hair regrowth in Middle Eastern men with early baldness, with better results in younger patients and certain types of baldness.
11 citations
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September 1988 in “Annals of Plastic Surgery” Topical minoxidil can help some men regrow hair, but results vary and may decline after a year.
16 citations
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July 1988 in “International Journal of Dermatology” The 2% minoxidil solution is safe and effective for treating male pattern baldness.
January 2022 in “Cosmoderma” Using oral minoxidil and dutasteride together can quickly increase hair growth and volume with minimal side effects.
January 2011 in “The Internet Journal of Pharmacology” Minoxidil is cost-effective for regrowing hair on the scalp's top but not the front, requiring ongoing use.
17 citations
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July 1988 in “International Journal of Dermatology” The 2% minoxidil solution is safe and effective for early male pattern baldness.
57 citations
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July 1987 in “Journal of The American Academy of Dermatology” Stopping minoxidil treatment resumes balding; continuous use needed for results.
55 citations
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February 1985 in “Archives of Dermatology” Minoxidil applied twice daily can help regrow hair in some people with hereditary baldness, with no serious side effects.
55 citations
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February 1985 in “Archives of Dermatology” Using minoxidil on the scalp can help grow hair for people with hereditary baldness.