Anti-Androgenetic Alopecia Effect of Policosanol from Chinese Wax by Regulating Abnormal Hormone Levels to Suppress Premature Hair Follicle Entry into the Regression Phase

Policosanol from Chinese wax has the potential to treat androgenetic alopecia by regulating hormone levels and preventing premature hair follicle regression, resulting in increased hair growth and thickness and reduced hair loss. Studies have found that it can reduce serum testosterone levels, inhibit 5α-reductase activity, and delay hair follicle regression. It may also promote hair follicle growth and prevent hair follicle cell death. Topical application has been shown to reduce hair loss and regulate hormone levels. The optimal concentration for treatment is 2% or 12.5 µg/mL. Overall, policosanol from Chinese wax shows promise as a natural and safe treatment for androgenetic alopecia.