Effect of Ethanol Extract of Plant Mixture on Hair Regeneration in Human Dermal Papilla Cells and C57BL/6J Mice

    Bo Huang, Bueom-Goo Kang, Zhiqiang Wang, Soon Sung Lim
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    TLDR A plant mixture extract helped grow hair by boosting cell growth and growth factors while blocking a hair loss-related enzyme.
    The study from December 3, 2015, demonstrated that a 30% ethanol extract of a plant mixture (EPM) containing various medicinal plants promoted hair growth by increasing the proliferation of human hair dermal papilla cells and inducing an early anagen phase in C57BL/6J mice. EPM was shown to significantly increase growth factors like IGF-1, VEGF, KGF, and HGF, and inhibit 5α-reductase activity, which is implicated in hair loss, in a dose-dependent manner. The study concluded that EPM could be a potential candidate for hair growth promotion, although the number of human cells or mice used in the experiments was not specified.
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