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    GlossarySystemic Absorption

    substance enters bloodstream and spreads throughout the body

    Systemic absorption refers to the process by which a substance, such as a medication or chemical, enters the bloodstream and is distributed throughout the body. This can occur through various routes, including oral ingestion, inhalation, or through the skin. Once in the bloodstream, the substance can exert its effects on different organs and tissues, which is crucial for treatments that need to reach systemic circulation to be effective.

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      a topical anti-androgen with less systemic involvement

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      Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity

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      community Ru with gloves because of Systemic absorption?

      in Research/Science  10 upvotes 1 year ago
      The conversation is about whether to use gloves when applying 5% RU58841 to avoid systemic absorption and if washing hands with water is sufficient. Users question the concern, noting it is applied to the scalp.

      community Efficacy and Systemic DHT Suppression of Topical Finasteride vs Dutasteride

      in General  122 upvotes 2 months ago
      Topical dutasteride may have limited absorption due to its higher molecular mass compared to finasteride, potentially affecting its efficacy in suppressing DHT locally. Microneedling might enhance dutasteride absorption, possibly offering stronger local DHT suppression with fewer systemic effects.

      community How much Minoxidil goes systemic?

      in Minoxidil  69 upvotes 1 week ago
      The conversation is about the systemic absorption of Minoxidil and the potential switch from topical to oral Minoxidil due to its effectiveness. The user considers oral Minoxidil after experiencing no side effects from a year of using 15% topical Minoxidil.

      community Solvent for topical fin with low absorption

      in Product  2 upvotes 1 year ago
      The conversation is about using distilled water as a solvent for topical finasteride to reduce systemic absorption. The user is considering avoiding ethanol and propylene glycol to achieve this.