Topical Finasteride Versus Topical Spironolactone in the Treatment of Androgenetic Alopecia

June 2020 in “ The Medical Journal of Cairo University ”

Ayman E. Yousef Ahmed S. Abdelshafy, Mohamed Salem Almabrouk

topical finasteride topical spironolactone androgenetic alopecia AGA Propecia spironolactone androgenic alopecia

From the encyclopedia

Frontline, gold standard treatment for combatting androgenic alopecia

powerful topical and oral anti-androgen used mostly by women

Studysummary In this study, topical spironolactone was found to be more effective than topical finasteride for treating androgenetic alopecia in both males and females, with fewer side effects compared to oral finasteride.

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Research cited in this study

4 / 4 results

research A Systematic Review of Topical Finasteride in the Treatment of Androgenetic Alopecia in Men and Women

23 citations , April 2018 in “PubMed”

This review finds preliminary evidence suggesting that topical finasteride may significantly reduce hair loss and increase hair counts in treating androgenetic alopecia, with a promising safety profile.

Combined Treatment with Oral Finasteride and Topical Minoxidil in Male Androgenetic Alopecia: A Randomized and Comparative Study in Chinese Patients

research Combined Treatment with Oral Finasteride and Topical Minoxidil in Male Androgenetic Alopecia: A Randomized and Comparative Study in Chinese Patients

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In this study, finasteride was found to be more effective than 5% minoxidil for treating male androgenetic alopecia in Chinese patients, with combination therapy showing the greatest improvement.

A Novel Finasteride 0.25% Topical Solution for Androgenetic Alopecia: Pharmacokinetics and Effects on Plasma Androgen Levels in Healthy Male Volunteers

research A Novel Finasteride 0.25% Topical Solution for Androgenetic Alopecia: Pharmacokinetics and Effects on Plasma Androgen Levels in Healthy Male Volunteers

50 citations , July 2014 in “International Journal of Clinical Pharmacology and Therapeutics”

This study found that both topical and oral finasteride significantly reduced plasma DHT after one week, with lower finasteride plasma exposure for the topical formulation.

research Understanding and Management of Female Pattern Alopecia

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This review discusses hair transplant techniques for female pattern hair loss and reports no new clinical results; it highlights the benefits of transplants combined with various treatments for improved hair density and styling options.