Determination of Estradiol and Progesterone Concentrations in Human Scalp Hair
January 2020
in “
Clinical and experimental obstetrics & gynecology
”
TLDR Hair levels of estradiol and progesterone are higher in premenopausal than postmenopausal women, but the difference isn't statistically significant, indicating the need for a better measurement method.
The study aimed to measure estradiol (E) and progesterone (P) concentrations in the scalp hair of premenopausal and postmenopausal women using a chemiluminescent enzyme immunoassay. It included 22 premenopausal women (mean age 30±4.8 years) and 17 postmenopausal women (mean age 62±8.1 years). Results showed higher mean E and P concentrations in premenopausal women compared to postmenopausal women, but the differences were not statistically significant. The study concluded that while hair E and P concentrations can be quantified by immunoassay, it may not be the optimal method, and further research is needed to find the best technique for measuring these hormones in scalp hair.