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research Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus

4350 citations , May 2012 in “Arthritis & Rheumatism”

This study found that the new SLICC classification criteria for systemic lupus erythematosus were more sensitive and resulted in fewer misclassifications than the current ACR criteria, although they had lower specificity.

research Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society* Clinical Practice Guideline

2170 citations , September 2017 in “The Journal of Clinical Endocrinology & Metabolism”

This updated guideline from the Endocrine Society highlights the importance of endocrinologists in providing safe and effective hormone regimens for gender-affirming care, especially for adolescents who have entered puberty.

research Organic Causes of Erectile Dysfunction in Men Under 40

2152 citations , November 2013 in “Urologia Internationalis”

This study reviews the significant prevalence of organic etiologies, especially vascular causes, in erectile dysfunction among men under 40 and emphasizes thorough evaluation and consideration of treatment options like exercise and PDE-5 inhibitors.

Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline

research Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline

1744 citations , August 2006 in “The Journal of Clinical Endocrinology and Metabolism”

This review discusses definitions of polycystic ovary syndrome and reports no new clinical results; the authors support using modified 1990 NIH criteria and acknowledge ongoing evolution as research advances.

research The Long-Term Effect of Doxazosin, Finasteride, and Combination Therapy on the Clinical Progression of Benign Prostatic Hyperplasia

1707 citations , December 2003 in “The New England Journal of Medicine”

Combination therapy of doxazosin and finasteride safely and effectively reduces benign prostatic hyperplasia progression risk.

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community Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect

126 upvotes 3 months ago

PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.

community Extra bonus of taking oral minoxidil 10 mg split morning niggt

in Minoxidil 61 upvotes 4 months ago

The user has been using oral minoxidil at 10 mg daily, split between morning and night, alongside finasteride for 7 years, and reports new hair growth at the temples. Many users express concern over the high minoxidil dosage, citing potential health risks, while others question the effectiveness and necessity of such a dose.

community EveryChem 3HP / PP30 page data vs NMR PDFs in their website : metadata mistake or document mismatch?

in Research/Science 15 upvotes 5 months ago

There is an inconsistency between the molecular weight and formula listed on EveryChem's product page and the analytical PDFs for 3HP and PP30, suggesting a possible error in the product description. Concerns are raised about EveryChem's business practices and lack of transparency in testing and manufacturing.

community EssenGen 6-Plus with PG Results - 12 Weeks (Update 2)

1192 upvotes 9 months ago

Significant hair regrowth was achieved using EssenGen 6-Plus with 6% minoxidil and 0.05% finasteride, along with Nizoral shampoo, over 12 weeks. No side effects were experienced, highlighting the benefits of a low dose.

community Evolution theory: AGA is your body trying to reduce the risk of prostate cancer by exposing your scalp to more UV

in Research/Science 9 months ago

Androgenic alopecia (AGA) might have evolved to reduce prostate cancer risk by increasing UV exposure to the scalp, but this theory is debated. Treatments like minoxidil and finasteride are used for AGA, though the exact causes and evolutionary reasons for hair loss are unclear.

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Learn

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learn Exosomes

Microscopic delivery system that sends growth-promoting signals to hair follicles

learn Estradiol

an estrogen promoting hair regrowth more commonly used in women

learn Ecklonia Cava

How does Ecklonia Cava help slow down hair loss in people with androgenetic alopecia? Ecklonia cava may slow hair loss by inhibiting the enzyme that converts testosterone to DHT.
Is Ecklonia Cava better taken orally or applied topically for thinning hair? There is no human trial of Ecklonia cava for hair loss by either route, so neither oral nor topical use is established; the published work is laboratory studies on human cells and topical studies in mice.
Can Ecklonia Cava reactivate dormant hair follicles and support new growth? Ecklonia Cava may support scalp health but lacks definitive evidence for reactivating hair follicles.

learn Ethanol

learn emu oil

learn Minoxidil

Minoxidil: the application and its effects counted in months Expect initial shedding in the first month, with visible results typically by three to six months.

learn Centella

Ever wonder why your hair doesn’t grow back thick anymore? Maybe your scalp needs better blood flow: centella could help. There is no clinical trial of centella asiatica for hair loss and no study measuring scalp blood flow in people using it; the only hair-related evidence is a 2017 cell-culture study. Centella products are cosmetics that may soothe an irritated scalp, and the link between scalp circulation and pattern hair loss is itself unproven.

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