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      PP405 Identity Research

      community PP405 Identity Research

      in Research  292 upvotes 2 weeks ago
      PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

      community 6 Months progress, and some second shed anxiety

      in Progress Pictures  10 upvotes 1 month ago
      The user shared progress pictures of their hair journey, noting good results after initial shedding but experiencing a second, more intense shed. They use topical Minoxidil twice daily, Tretinoin at night, oral finasteride daily, and ketoconazole shampoo weekly.

      community Progress- 3 months, 5% Minoxidil, 0.1% Finasteride

      in Is this regrowth?  232 upvotes 2 months ago
      The user experienced significant hair loss after stopping a treatment of 5% Minoxidil and 0.1% Finasteride, which they had used from December 2021 to January 2024. They resumed the treatment in April 2025, hoping for regrowth, and are considering additional treatments like transplants and steroid injections.

      community I have been on finasteride for 9 months. (6 months on 0.25 mg, 3 months into 0.5 mg daily) here are the progress pictures.

      in Progress Pictures  273 upvotes 3 months ago
      A user shared progress pictures after 9 months on finasteride, starting with 0.25 mg and increasing to 0.5 mg daily, noting improved hair density, especially at the crown, with initial side effects that resolved after the first month. The discussion includes user experiences with finasteride, concerns about side effects, and alternative treatments like rosemary oil and platelet-rich plasma therapy.