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    Glossary Estradiol

    potent estrogen hormone primarily produced in the ovaries

    Estradiol, also known as 17β-Estradiol or E2, is a potent estrogen hormone primarily produced in the ovaries. It plays a crucial role in regulating the menstrual cycle, reproductive system, and secondary sexual characteristics in females. Additionally, estradiol has significant effects on various tissues, including bone, skin, and hair, influencing growth and maintenance.

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    1. Testosterone modulation of seizure susceptibility is mediated by neurosteroids 3α-androstanediol and 17β-estradiol Neuroscience · 2004 · 136 citations
    2. Puberty in Boys: Correlation of Plasma Levels of Gonadotropins (LH, FSH), Androgens (Testosterone, Androstenedione, Dehydroepiandrosterone and Its Sulfate), Estrogens (Estrone and Estradiol) and Progestins (Progesterone and 17-Hydroxyprogesterone) The Journal of Clinical Endocrinology & Metabolism · 1975 · 96 citations
    3. Estrus, ovulation, and serum progesterone, estradiol, and LH concentrations in mares after an increased photoperiod during winter. PubMed · 1977 · 83 citations
    4. 17β-Estradiol and ICI-182780 regulate the hair follicle cycle in mice through an estrogen receptor-α pathway 2000 · 71 citations
    5. Cellular actions of testosterone in vascular cells: Mechanism independent of aromatization to estradiol Steroids · 2012 · 55 citations
    6. Differential Suppression of Testosterone and Estradiol in Hirsute Women With the Superactive Gonadotropin-Releasing Hormone Agonist Leuprolide* The Journal of Clinical Endocrinology & Metabolism · 1988 · 49 citations
    7. Hormonal Treatment of Transgender Women with Oral Estradiol Transgender health · 2018 · 37 citations
    8. Consecutive Cyproterone Acetate and Estradiol Treatment in Late-Pubertal Transgender Female Adolescents ˜The œjournal of sexual medicine · 2017 · 36 citations
    9. Presentation of a meningioma in a transwoman after nine years of cyproterone acetate and estradiol intake: case report and literature review Gynecological Endocrinology · 2017 · 34 citations
    10. Effects of 17-β-Estradiol and ICI 182 780 on Hair Growth in Various Strains of Mice Journal of Investigative Dermatology Symposium Proceedings · 1999 · 32 citations
    11. Prevention and treatment of experimental prostate cancer in lobund-wistar rats. I. Effects of estradiol, dihydrotestosterone, and castration 1989 · 31 citations
    12. Estrus, Ovulation, and Serum Progesterone, Estradiol, and LH Concentrations in Mares After an Increased Photoperiod During Winter American Journal of Veterinary Research · 1977 · 25 citations
    13. In vitro effects of testosterone, dihydrotestosterone and estradiol on cell growth of human hair bulb papilla cells and hair root sheath fibroblasts. Acta Dermato Venereologica · 1990 · 22 citations
    14. Testosterone Metabolism in Human Skin Cells in vitro and Its Interaction with Estradiol and Dutasteride Skin pharmacology and physiology · 2003 · 21 citations
    15. Weak correlations between serum and cerebrospinal fluid levels of estradiol, progesterone and testosterone in males BMC Neuroscience · 2019 · 19 citations
    16. 17β-Estradiol Enhances Vascular Endothelial Growth Factor Production and Dihydrotestosterone Antagonizes the Enhancement via the Regulation of Adenylate Cyclase in Differentiated THP-1 Cells 2002 · 18 citations
    17. Studies on the persistence of estradiol benzoate and nortestosterone decanoate in hair of cattle following treatment with growth promoters, determined by ultra-high-performance liquid chromatography–tandem mass spectrometry Journal of Chromatography A · 2009 · 18 citations
    18. Noncontraceptive benefits of the estradiol valerate/dienogest combined oral contraceptive: a review of the literature International Journal of Women's Health · 2014 · 16 citations
    19. EFFECT OF ESTRADIOL LOCALLY APPLIED TO ABNORMAL SKIN Archives of Dermatology · 1943 · 14 citations
    20. Within-person changes of cortisol, dehydroepiandrosterone, testosterone, estradiol, and progesterone in hair across pregnancy, with comparison to a non-pregnant reference group Comprehensive psychoneuroendocrinology · 2020 · 12 citations
    21. Estrone Sulfate Source of Estrone and Estradiol Formation in Isolated Human Hair Roots: Identification of a Pathway Linked to Hair Growth Phase and Subject to Site-, Gender-, and Age-Related Modulations The Journal of Clinical Endocrinology & Metabolism · 2014 · 11 citations
    22. Estradiol‐induced alopecia in five dogs after contact with a transdermal gel used for the treatment of postmenopausal symptoms in women Veterinary Dermatology · 2015 · 10 citations
    23. The E6/E7 oncogenes of human papilloma virus and estradiol regulate hedgehog signaling activity in a murine model of cervical cancer Experimental Cell Research · 2019 · 9 citations
    24. Effects of testosterone, dihydrotestosterone and estradiol on growth of human hair outer root sheath keratinocytes in vitro Archives of Dermatological Research · 1991 · 9 citations
    25. Effect of 150 kHz electromagnetic radiation on the development of polycystic ovaries induced by estradiol Valerate in Sprague Dawley rats Journal of Ovarian Research · 2021 · 6 citations
    26. Ultra-low dose estradiol and dydrogesterone for the treatment of menopausal symptoms in a pooled, multi-ethnic population Maturitas · 2024 · 5 citations
    27. Reversal of the hair loss phenotype by modulating the estradiol-ANGPT2 axis in the mouse model of female pattern hair loss Journal of Dermatological Science · 2018 · 5 citations
    28. Effects of testosterone, dihydrotestosterone and estradiol on the growth behavior of cultured hair bulb papilla cells and root sheath fibroblasts 1989 · 5 citations
    29. Efficacy of Topical Finasteride 0.5% vs 17α-Estradiol 0.05% in the Treatment of Postmenopausal Female Pattern Hair Loss: A Retrospective, Single-Blind Study of 119 Patients Dermatology practical & conceptual · 2020 · 4 citations
    30. [Acceptability, tolerance and quality of life impact of cyproterone acetate treatment in female hirsutism. Comparison of 2 protocols in combination with oral or transdermal estradiol]. PubMed · 1994 · 4 citations