research Testosterone Metabolism in the Skin
This review discusses testosterone metabolism in human skin and its role in androgenetic skin disorders, suggesting that temporary increases in dihydrotestosterone may lead to these conditions.
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5 / 1000+ resultsresearch Testosterone metabolism in the skin. A review of its function in androgenetic alopecia, acne vulgaris, and idiopathic hirsutism including recent studies with antiandrogens
This review discusses testosterone metabolism in human skin and its link to androgenetic alopecia, acne vulgaris, and idiopathic hirsutism, but it presents no new results.
research Different patterns of 5α-reductase expression, cellular distribution, and testosterone metabolism in human follicular dermal papilla cells
Androgen effects on hair follicles vary by skin area.
research Testosterone Metabolism in Human Skin Cells in vitro and Its Interaction with Estradiol and Dutasteride
This study found that dutasteride completely suppressed the formation of 5alpha-dihydro metabolites in cultured human skin cells, suggesting its potential use in acne and androgenetic alopecia.
research Is the metabolism of testosterone to 5α-dihydrotestosterone required for androgen action in the skin?
This article discusses whether testosterone's metabolism to 5α-dihydrotestosterone is necessary for androgenic effects in the skin but reports no new experimental results.
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5 / 1000+ resultscommunity Prolonged shedding over last 15 months
The user has been experiencing prolonged hair shedding despite using Dutasteride, Minoxidil, and topical Finasteride, with blood tests showing high free testosterone and low SHBG. Suggestions include adjusting Minoxidil dosage, considering topical anti-androgens like RU58841, and addressing metabolic factors to increase SHBG.
community Ray Peat: Testosterone Isn’t the Culprit, Prolactin and Cortisol Drive Hair Loss (2016)
Prolactin and cortisol are identified as key factors in hair loss, with stress hormones impacting hair shedding. Finasteride and minoxidil are effective treatments, while DHT's role and individual sensitivity are significant factors.
community Testosterone increased after six months of finasteride
A 23-year-old male experienced an increase in testosterone levels after taking 1 mg of finasteride daily for six months, with no significant side effects reported. Users discussed how finasteride inhibits DHT, leading to increased testosterone, and debated the psychological versus physiological effects of the medication.
community Testosterone in Reference Range Doesn't Cause Hair Loss
Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.
community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens.
A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.
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3 / 10 results- Could bicalutamide help trans women regrow hair lost to testosterone? No study has tested bicalutamide for hair regrowth in trans women. In cisgender women the only randomized trial found it added nothing to minoxidil, and it is an off-label prescription drug that requires liver monitoring.
learn Dutasteride
5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride
learn Spironolactone
Blood-pressure and diuretic drug with anti-androgen effects
learn Bicalutamide
Clinics
6 / 13 results- Hair Loss TreatmentsTestosterone ReplacementPlantation, FL · US
- Hair TransplantTestosterone Centers of TexasFrisco, TX · US
- Hair Loss TreatmentsTestosterone Therapy Fort LauderdaleFort Lauderdale, FL · US
- Hair Loss TreatmentsMedClub Testosterone & Bioidentical HormonesWest Palm Beach, FL · US
- Hair Loss TreatmentsReady Testosterone and Men's Health ClinicHouston, TX · US
- Hair Loss TreatmentsSoCal Testosterone ClinicLos Angeles, CA · US
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