research Studies on Neurosteroids XXIV: Determination of Neuroactive Androgens, Androsterone and 5α-Androstane-3α,17β-Diol, in Rat Brain and Serum Using Liquid Chromatography–Tandem Mass Spectrometry
The methods accurately measured brain androgens, showing most 5α-androstane-3α,17β-diol comes from outside the brain, while androsterone is both transported and made in the brain.