research Androgenetic Alopecia in Men and Women
Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.
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research Natural Bioactive Compounds as Potential Sources for Alleviation and Treatment of Androgenetic Alopecia: A Research Advance
Natural compounds from Chinese herbs may safely promote hair growth and treat common hair loss.
research Effects of Non-Contingent Cocaine on 3alpha-Androstanediol: Disruption of Male Sexual Behavior
Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.
research Antiandrogenic Activities of Glycyrrhiza Glabra in Male Rats
Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.
research Expression of Type 1 5α-Reductase and Metabolism of Testosterone in Reconstructed Human Epidermis: A New Model for Screening Skin-Targeted Androgen Modulators
The study created a new method to test drugs that affect hormone processing in skin.
research Methods Of Hair Restoration For Men And Women
Various hair restoration methods can effectively promote hair growth.
research Is The Metabolism Of Testosterone To 5α-Dihydrotestosterone Required For Androgen Action In The Skin?
Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.
research Testosterone Metabolism in Human Skin Cells In Vitro and Its Interaction with Estradiol and Dutasteride
Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.
research The Metabolism of Testosterone by Dermal Papilla Cells Cultured from Scalp Follicles of Men with Androgenetic Alopecia
Testosterone metabolism in balding scalp cells may not be the main cause of hair loss.
research Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia
Too much androgen can cause hair loss; finasteride may help.
research 5α-Metabolism in Finasteride-Treated Subjects and Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency
Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.
research Peripheral Androgens And The Role Of Androstanediol Glucuronide
Androstanediol glucuronide is a reliable marker for hirsutism in women.
research Considerations on Hair Research and Hair Growth
The document concludes that hair biology is complex and there are still unanswered questions about hair loss and follicle changes.
research Effects of Chronic Inhibition of Testosterone Metabolism on Cardiac Remodeling After Ischemia/Reperfusion-Induced Myocardial Damage in Gonadectomized Rats
Testosterone reduces heart damage and inflammation after injury.
research Testosterone Metabolism in the Skin: A Review of Its Function in Androgenetic Alopecia, Acne Vulgaris, and Idiopathic Hirsutism Including Recent Studies with Antiandrogens
Testosterone affects hair loss, acne, and excessive hair growth, and antiandrogens can help treat these conditions.
research Molecular Interactions of Natural and Synthetic Steroids in Female Hamsters’ Flank Organs
Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.
research Alterations in Androgen Conjugate Levels in Women and Men with Alopecia
People with hair loss may have different levels of certain hormones due to changes in hormone processing.
research Testosterone Metabolism in the Skin
Increased DHT formation in skin can cause hair loss, acne, and excessive hair growth, and antiandrogens might treat these conditions.
research The Metabolism and Control Mechanism of Human Hair Follicles
Human hair follicles have a unique metabolism that changes between growth stages and may contribute to baldness.
research Prostaglandin D2 Enhances Testosterone Metabolism by ROS-Mediated Altered Redox Potential in Keratinocytes
Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.
research In Vivo Uptake and Metabolism of Testosterone by the Skin and Other Tissues of the Rat
Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.
research Human Androgenic Steroids Affect Growth of Dermatophytes In Vitro
Androgenic steroids can slow down or stop the growth of certain skin fungi.
research Transcriptomic Profiling in Silurana Tropicalis Testes Exposed to Finasteride
Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.
research 5-Alpha-Dihydrotestosterone Metabolism and Its Relationship with Middle-Phalangeal Hair and Serum Concentrations in Healthy Men
Certain finger length ratios and body hair patterns may predict side effects from birth control pills in women.
research Original Research—Endocrinology: Comparison of the Steady-State Pharmacokinetics, Metabolism, and Variability of a Transdermal Testosterone Patch Versus a Transdermal Testosterone Gel in Hypogonadal Men
The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.
research Recent Developments in Alopecias
Recent hair loss research shows some progress, especially in understanding male pattern baldness, but effective treatments for many types of hair loss are still lacking.
research Hair Follicles and Associated Glands as Androgen Targets
Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.
research The Effect of Minocycline on the Metabolism of Androgens by Human Oral Periosteal Fibroblasts and Its Inhibition by Finasteride
Minocycline may cause hair loss by increasing DHT levels, but finasteride can help counteract this effect.
research Prostaglandin D2-Enhanced Testosterone Metabolism in Human Keratinocytes Is Mediated by Reactive Oxygen Species
Prostaglandin D2 increases testosterone levels in skin cells through reactive oxygen species, not enzymes, which could lead to new hair loss treatments.
research Role of 5α-Reductase in Health and Disease
5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.