15 citations
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July 2017 in “PubMed” This study observed that injecting a combination of human cultured dermal papilla and epithelial cells induced hair growth in a mouse model.
January 2011 in “Medical Journal of National Defending Forces in Northwest China” This study found that hypodermic injections of human dermal papilla cells conditioned medium led to hair regrowth in women with androgenetic alopecia, with an effective rate of 83.33%.
January 2010 in “International Journal of Dermatology and Venereology” This review discusses the relationship between dermal papilla cells and androgenetic alopecia, noting the involvement of androgens and mental factors, but reports no new clinical results.
January 2009 in “Chinese Journal of Aesthetic Medicine” This study found that treatment with human dermal papilla cells conditioned medium resulted in an 81.25% total effective rate and a 62.50% cure rate for androgenetic alopecia.
13 citations
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June 2008 in “Springer eBooks”
41 citations
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June 2006 in “Journal of Investigative Dermatology” This study identified three genes with significantly higher expression in androgen-sensitive beard dermal papilla cells compared to androgen-insensitive scalp cells, suggesting potential novel signaling pathways in hair follicles.
231 citations
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December 1999 in “Journal of Investigative Dermatology” This study found that the volume of a hair follicle's dermal papilla is strongly correlated with its size, primarily due to the number of cells it contains and the volume of extracellular matrix.
227 citations
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January 1998 in “Journal of Endocrinology” This study found that dermal papilla cells from balding scalp hair follicles have significantly higher levels of androgen receptors than those from non-balding follicles, supporting their in vivo androgen response.
19 citations
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March 1996 in “British Journal of Dermatology” This study found that dermal papilla cells from balding follicles exhibit distinct growth characteristics compared to non-balding cells, suggesting their potential as a model for understanding androgenetic alopecia.
48 citations
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April 1995 in “PubMed” This study found that dermal papilla cells from beard and axillary hair follicles can produce androgen-dependent factors that stimulate proliferation in adjacent follicular epithelial cells under testosterone influence.
34 citations
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July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that androgens influence hair follicle behavior via the dermal papilla, using evidence from human and red deer cells with differing androgen responses as models.