The Metabolism of Testosterone by Dermal Papilla Cells Cultured from Scalp Follicles of Men with Androgenetic Alopecia

This document is a collection of poster presentations from a dermatology conference. One presentation describes the establishment and characterization of a Merkel cell carcinoma cell line from a tumor on the scalp of a Japanese woman. Another presentation investigates the induction of terminal differentiation of squamous cell carcinoma by bufalin. A third presentation explores the effect of cyclosporin, minoxidil, testosterone, estradiol, and corticosteroid on hair growth in nude mice. The fourth and final presentation discusses the metabolism of testosterone by dermal papilla cells cultured from scalp follicles of men with androgenetic alopecia. The study found that although some 5a-reductase activity was present in balding DP cells, the small amounts of DHT present may suggest it is not the active androgen in balding follicles.