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    Glossary Cyclosporine

    immunosuppressive drug used to prevent organ rejection and treat autoimmune diseases

    Cyclosporine, also known as cyclosporin A or CsA, is an immunosuppressive drug primarily used to prevent organ transplant rejection and to treat certain autoimmune conditions. It works by inhibiting the activity of T-cells, a type of white blood cell involved in the immune response. In dermatology, cyclosporine has been explored for its potential to treat severe cases of alopecia areata, a condition characterized by sudden hair loss.

    Research

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      research The use of cyclosporine in dermatology: Part I

      131 citations , November 2010 in “Journal of the American Academy of Dermatology”
      This article reviews cyclosporine's mechanism, uses, and dosing in dermatology, but reports no new clinical findings, focusing instead on helping dermatologists integrate it safely into their practice.

      research Toxicity of the immune suppressant cyclosporin A in the rat

      116 citations , October 1982 in “The Journal of Pathology”
      This study found that high-dose Cyclosporin A in rats led to significant functional and structural changes, including liver, kidney, and immune system alterations, along with behavioral and hematological effects.

      research Cyclosporin A: a new drug in the field of canine dermatology

      84 citations , March 2004 in “Veterinary Dermatology”
      In randomized controlled trials, this research reports that cyclosporin is as effective as glucocorticoids for treating canine atopic dermatitis and has potential benefits for other immune-mediated skin conditions in dogs.

      research Topical Cyclosporine in Alopecia Areata

      69 citations , February 1987 in “Archives of Dermatology”
      This case report describes the topical application of cyclosporine in a man with alopecia universalis, which showed hair regrowth after 10 months of daily use, except where limited by a congenital nevus.
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      community OND-1 "Cyclosporine A” New hair loss treatment

      in Research/Science  28 upvotes 5 months ago
      Orient Bio is developing a PLGA formulated version of Cyclosporine A to stimulate hair growth without its immunosuppressant effects. Users discuss various treatments like Clascoterone, PP405, minoxidil, and tacrolimus, expressing hope for new developments and sharing personal experiences with these treatments.

      community What happened to the 40mg dutasteride daily and Cyclosporine dude?

      in Chat  40 upvotes 1 year ago
      A user previously claimed to take 40mg of dutasteride daily and planned to try Cyclosporine, but their account and comments have since been deleted, raising concerns about their well-being. Other users discussed the risks and effectiveness of high doses of dutasteride, with some sharing their own experiences using dutasteride, finasteride, and minoxidil for hair loss treatment.

      community Forgotten 'Total Revival' Stack

      in Research/Science  42 upvotes 1 year ago
      Cyclosporine A is discussed as a powerful hair growth stimulant, potentially more effective than minoxidil, but concerns about safety and side effects, including cancer risk, limit its use. The conversation highlights the need for further research and experimentation with topical application, despite its risks.

      community The DEFINITIVE cure for hairloss

       285 upvotes 1 year ago
      The conversation humorously suggests using immunosuppressants like ciclosporine and oral minoxidil for hair regrowth, with a satirical plan involving hair transplants from family members. It highlights the side effects and impracticality of such treatments, emphasizing the post's satirical nature.

      community RT1640 - Gray Hair Reversal Recipe

       3 upvotes 4 years ago
      The conversation discusses a hair loss treatment formulation containing cyclosporin, minoxidil, and tacrolimus, and mentions ongoing research on hair color reversal. The treatment showed high efficacy in restoring hair color in trials with 40 to 50 people.
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