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GlossaryCyclosporine

immunosuppressive drug used to prevent organ rejection and treat autoimmune diseases

Cyclosporine, also known as cyclosporin A or CsA, is an immunosuppressive drug primarily used to prevent organ transplant rejection and to treat certain autoimmune conditions. It works by inhibiting the activity of T-cells, a type of white blood cell involved in the immune response. In dermatology, cyclosporine has been explored for its potential to treat severe cases of alopecia areata, a condition characterized by sudden hair loss.

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research Drug-Induced Hair Loss and Hair Growth

147 citations , April 1994 in “Drug Safety”

Some drugs can cause hair loss or increase hair growth, but these effects are usually reversible when the drug is stopped.

research Three Cases of Immune-Mediated Adnexal Skin Disease Treated with Cyclosporin

36 citations , January 2006 in “Veterinary Dermatology”

Cyclosporin effectively and safely treated skin diseases in three pets with no side effects.

research Acne Keloidalis Nuchae in Renal Transplant Patients Receiving Tacrolimus and Sirolimus

6 citations , April 2016 in “Australasian journal of dermatology”

Renal transplant patients on tacrolimus and sirolimus may develop acne keloidalis nuchae.

research Effect of Cyclosporin on Hair-Existing Area of Nude Mice

10 citations , July 1994 in “Journal of Dermatological Science”

Cyclosporin extends hair growth in mice, but high-dose corticosteroids block this effect.

research Therapeutic Synergy Between Contact Dermatitis from a Wig-Fixing Device and Tofacitinib on Alopecia Areata

4 citations , September 2018 in “The Journal of Dermatology”

A man's hair regrew from alopecia areata after using tofacitinib and experiencing contact dermatitis from a wig device.

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community RT1640 - Gray Hair Reversal Recipe

in Research/Science 3 upvotes 3 years ago

The conversation discusses a hair loss treatment formulation containing cyclosporin, minoxidil, and tacrolimus, and mentions ongoing research on hair color reversal. The treatment showed high efficacy in restoring hair color in trials with 40 to 50 people.

community Making your own RT1640 in China

in Research/Science 4 years ago

RT1640, a combination of cyclosporin A, minoxidil, and RT175, is discussed as a potential treatment for hair regrowth and repigmentation. The unique formulation aims to enhance hair follicle growth and restore hair pigment without the negative side effects of immunosuppressants.

community Forgotten 'Total Revival' Stack

in Research/Science 42 upvotes 10 months ago

Cyclosporine A is discussed as a powerful hair growth stimulant, potentially more effective than minoxidil, but concerns about safety and side effects, including cancer risk, limit its use. The conversation highlights the need for further research and experimentation with topical application, despite its risks.

community JW Pharmaceutical shows superiority of 'JW0061' in hair growth over existing treatments in US

in Research/Science 99 upvotes 1 year ago

JW0061 shows superior hair growth results compared to existing treatments, with significant increases in hair follicles. The Wnt/β-catenin pathway is crucial for hair growth, and JW0061 activates this pathway effectively.

community Is itching related to hair loss?

in Treatment 54 upvotes 3 years ago

Hair loss, which is sometimes accompanied by itching. Treatments discussed include Minoxidil, finasteride, RU58841 and ketocazole shampoo.

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