Noncontraceptive Benefits of the Estradiol Valerate/Dienogest Combined Oral Contraceptive: A Review of the Literature

August 2014 in “ International Journal of Women's Health ”

Rossella E. Nappi, Marco Serrani, Jeffrey T. Jensen

estradiol valerate dienogest combined oral contraceptive hormone withdrawal-associated symptoms acne hyperandrogenism polycystic ovary syndrome PCOS E₂V DNG COC

TLDR The estradiol valerate/dienogest oral contraceptive helps with heavy periods, may improve acne and symptoms in PCOS, and doesn't affect sexual function.

The document reviews the noncontraceptive benefits of the estradiol valerate/dienogest (E₂V/DNG) combined oral contraceptive, emphasizing its effectiveness in treating heavy menstrual bleeding (HMB), with a significant reduction in menstrual blood loss (MBL) and improvements in quality of life. E₂V/DNG is also noted to reduce hormone withdrawal-associated symptoms and may have positive effects on acne and hyperandrogenism in women with polycystic ovary syndrome (PCOS). However, the document calls for larger randomized controlled trials to confirm these benefits. Overall, E₂V/DNG is presented as a beneficial alternative for women who experience hormone withdrawal symptoms with traditional combined oral contraceptives (COCs) and does not negatively impact sexual function.

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research Non-Contraceptive Benefits of Oral Hormonal Contraceptives

83 citations, December 2012 in “International journal of endocrinology and metabolism/International journal of endocrinology and metabolism.”

Oral contraceptives provide various health benefits beyond birth control, including managing menstrual issues, skin conditions, pain, and reducing the risk of certain cancers.

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research Noncontraceptive Benefits of the Estradiol Valerate/Dienogest Combined Oral Contraceptive: A Review of the Literature

16 citations, August 2014 in “International Journal of Women's Health”

The estradiol valerate/dienogest oral contraceptive helps with heavy periods, may improve acne and symptoms in PCOS, and doesn't affect sexual function.