Prevention and Treatment of Experimental Prostate Cancer in Lobund-Wistar Rats: Effects of Estradiol, Dihydrotestosterone, and Castration

    January 1989 in “ ˜The œProstate/˜The œprostate ”
    Morris Pollard, Phyllis H. Luckert, David Snyder
    Studysummary This study found that early treatment with estradiol or dihydrotestosterone significantly reduced prostate adenocarcinoma development in Lobund-Wistar rats, while later treatments were ineffective.
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    Research cited in this study 1

    1. The Dihydrotestosterone Hypothesis of Prostate Cancer and Its Therapeutic Implications The Prostate · 1986