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Synthesis of 5,6,6-[2H3]Finasteride and Quantitative Determination of Finasteride in Human Plasma at Picogram Level by an Isotope-Dilution Mass Spectrometric Method

research Synthesis of 5,6,6-[2H3]Finasteride and Quantitative Determination of Finasteride in Human Plasma at Picogram Level by an Isotope-Dilution Mass Spectrometric Method

20 citations , December 1995 in “Journal of Chromatography B: Biomedical Sciences and Applications”

Accurate method measures finasteride levels in human plasma using gas chromatography-mass spectrometry.

research Comparative GC-MS Based In Vitro Assays of 5α-Reductase Activity Using Rat Liver S9 Fraction

8 citations , March 2012 in “Mass spectrometry letters”

The S9 fraction with GC-IDMS is effective for measuring 5α-reductase activity.

research Revisiting Hyper- and Hypo-Androgenism by Tandem Mass Spectrometry

27 citations , April 2013 in “Reviews in endocrine and metabolic disorders”

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

research Elemental Hair Analysis: A Review of Procedures and Applications

96 citations , September 2017 in “Analytica Chimica Acta”

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

research A Stability Indicating UPLC Method for Finasteride and Its Related Impurities

3 citations , January 2012 in “American Journal of Analytical Chemistry”

A new method effectively analyzes Finasteride and its impurities, even under stress conditions.

View more "isotope-dilution mass spectrometry" in research →

Community Join

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community BREAKTHROUGH: I’m a radiochemist and discovered a radioactive isotope scalp serum that OUTPERFORMS Minoxidil and 5-AR inhibitors! (Lab Data Inside)

in Satire 6 months ago

A satirical post where someone claims to have developed a radioactive isotope scalp serum using Polonium-210 that outperforms Minoxidil and finasteride for hair regrowth. The serum reportedly stimulates DNA repair in hair follicles, leading to significant hair density increase, but the post is met with skepticism and concerns about safety.

community Sugar and Hair loss connections

in Research/Science 41 upvotes 6 months ago

High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.

community Dutasteride Literally Saves Your Hair

in Finasteride/Dutasteride 101 upvotes 1 year ago

Dutasteride significantly reduces scalp DHT levels and can save hair, though shedding is part of the process. Some users report success with dutasteride, while others struggle despite using it along with finasteride and oral minoxidil.

community Why does it seem everyone favors finasteride over dutasteride?

in Female 62 upvotes 1 year ago

The conversation discusses preferences for hair loss treatments, specifically finasteride over dutasteride. Users share personal experiences, cost considerations, FDA approval status, and potential side effects, with some switching between treatments to find what works best for them.