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5 / 1000+ results![Synthesis of 5,6,6-[2H3]finasteride and quantitative determination of finasteride in human plasma at picogram level by an isotope-dilution mass spectrometric method](/images/research/0026b639-99a8-455a-a986-c39aa65abfa9/small/2087.jpg)
research Synthesis of 5,6,6-[2H3]finasteride and quantitative determination of finasteride in human plasma at picogram level by an isotope-dilution mass spectrometric method
Accurate method measures finasteride levels in human plasma using gas chromatography-mass spectrometry.
![Optimisation of microstructured biodegradable finasteride formulation for depot parenteral application](/images/research/e10f31f4-92ba-4018-b72d-1679f3c4fc0c/small/3760.jpg)
research Optimisation of microstructured biodegradable finasteride formulation for depot parenteral application
Improved finasteride formula allows slow, sustained release and better absorption for patients.
research Design, Synthesis, and Biological Characterization of Metabolically Stable Selective Androgen Receptor Modulators
Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.
![Recent advances in nanocarrier-loaded gels: Which drug delivery technologies against which diseases?](/images/research/76cf5700-b944-4ef7-9215-2ecdf9bd2294/small/34332.jpg)
research Recent advances in nanocarrier-loaded gels: Which drug delivery technologies against which diseases?
Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.
![Progesterone, neurosteroids, and the hormonal basis of catamenial epilepsy](/images/research/063af830-e5f9-486d-a26d-f397e40aa68e/small/20464.jpg)
research Progesterone, neurosteroids, and the hormonal basis of catamenial epilepsy
Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.
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5 / 25 resultscommunity FCE 28260: A Forgotten 5α-Reductase Inhibition
FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
community Is this hierarchy of topical anti androgens accurate?
User on fin, minox, and ketoconazole seeks to add another topical anti-androgen. Hierarchy of effectiveness: 1. RU55841, 2. Fluridil - Eucapil, 3. CB-03-01 - Breezula, 4. Ketoconazole; alfatradiol suggested as addition.
community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp
Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.
community drinking topical minoxidil – extreme hair growth everywhere
At this point.
In this conversation, users discussed the risks of drinking topical minoxidil and suggested alternative treatments such as obtaining a prescription for oral minoxidil or finasteride.
community 15 Week Update of Oral Consumption of Topical Minoxidil. 3 drops Keeps 5% (3.75mg) 2x per day with comparison.
CumShotDiva's update on using topical minoxidil orally in an attempt to regrow hair, which has been met with both support and criticism from other users. The conversation includes discussion of possible side effects and the efficacy of this approach.