Selective and Rapid Determination of Tadalafil and Finasteride Using Solid Phase Extraction by High Performance Liquid Chromatography and Tandem Mass Spectrometry

    Nagaraju Pappula, Balaji Kodali, Peda Varma Datla
    Studysummary This study validated a highly selective and fast LC–MS/MS method for accurately measuring levels of tadalafil and finasteride in human plasma, adhering to international bioanalytical guidelines.
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    Research cited in this study 9

    1. Determination of Finasteride in Human Serum by LC-MS/MS 분석과학 · 2011
    2. Determination of Finasteride in Human Plasma by Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry with Flow Rate Gradient European Journal of Drug Metabolism and Pharmacokinetics · 2010
    3. Polarographic Behavior and Determination of Finasteride Farmaco · 2003
    4. LC Determination of Finasteride and Its Application to Storage Stability Studies Journal of Pharmaceutical and Biomedical Analysis · 2001
    5. Determination of Finasteride in Human Plasma by Liquid-Liquid Extraction and High-Performance Liquid Chromatography Journal of Chromatography B: Biomedical Sciences and Applications · 2000
    6. Finasteride in Biological Fluids: Extraction and Separation by a Graphitized Carbon Black Cartridge and Quantification by High-Performance Liquid Chromatography Journal of Chromatography B: Biomedical Sciences and Applications · 1997
    7. High-Performance Liquid Chromatographic Determination of Finasteride in Human Plasma Using Direct Injection with Column Switching Journal of Chromatography B: Biomedical Sciences and Applications · 1996
    8. Clinical Pharmacokinetics and Pharmacodynamics of Finasteride Clinical Pharmacokinectics · 1996
    9. The Effect of Finasteride in Men with Benign Prostatic Hyperplasia The New England Journal of Medicine · 1992

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