TLDR Valid method measures finasteride in plasma, simple, fast, and affordable.
This document presents a validated method for measuring the concentration of finasteride in human plasma using liquid-liquid extraction and high-performance liquid chromatography. The method is simple, rapid, and cost-effective, with a sensitivity range of 4-300 ng/ml. The study involved 26 healthy volunteers who received a single oral dose of 10 mg of finasteride. The proposed method is suitable for pharmacokinetic studies and the samples were stable for at least 6 weeks at -18°C.
Cited in this study
6 / 6 results
17 citations
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May 1997 in “Journal of Chromatography B: Biomedical Sciences and Applications” Method accurately measures finasteride in human plasma.
29 citations
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February 1996 in “Journal of Chromatography B: Biomedical Sciences and Applications” New method detects finasteride in plasma quickly and accurately without clean-up.
![Synthesis of 5,6,6-[2H3]Finasteride and Quantitative Determination of Finasteride in Human Plasma at Picogram Level by an Isotope-Dilution Mass Spectrometric Method](/images/research/0026b639-99a8-455a-a986-c39aa65abfa9/small/2087.jpg)
20 citations
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December 1995 in “Journal of Chromatography B: Biomedical Sciences and Applications” Accurate method measures finasteride levels in human plasma using gas chromatography-mass spectrometry.
45 citations
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August 1994 in “Journal of Chromatography B: Biomedical Sciences and Applications” Method detects finasteride in plasma and semen with high sensitivity and accuracy.
86 citations
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July 1993 in “Drugs” Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.
19 citations
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May 1991 in “Journal of Chromatography B: Biomedical Sciences and Applications” Reliable method detects finasteride in human plasma at low doses.
