Low-Dose (2.5 mg/Day) Finasteride Treatment in Hirsutism

January 2003 in “ Gynecological Endocrinology ”

Fahri Bayram, Iptisam Ipek Muderris, Muhammet Güven, Bülent Özçelik, Fahrettin Kelestimur

finasteride hirsutism hormone levels Propecia

Studysummary In this study, low-dose finasteride (2.5 mg/day) significantly reduced hirsutism scores in women over 12 months without significant hormonal changes or serious side effects.

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The study evaluated the effectiveness of low-dose (2.5 mg/day) finasteride in treating hirsutism in women. The study involved 29 patients who received 2.5 mg finasteride once a day over a period of 12 months. The hirsutism score decreased significantly from a mean of 18.4 ± 4.6 to 8.4 ± 4.2 during the study, with a 55.7 ± 14.9% reduction in hirsutism score at 12 months. No significant differences in hormone levels or serious side-effects were observed during the treatment. The study concluded that low-dose finasteride is a cost-effective and well-tolerated therapeutic agent that can be used in place of high-dose finasteride in the treatment of hirsutism.

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Research cited in this study

9 / 9 results

research Finasteride Treatment for One Year in 35 Hirsute Patients

27 citations , July 2009 in “Experimental and Clinical Endocrinology & Diabetes”

This study found that finasteride significantly improved hirsutism scores in women over 12 months and was well-tolerated with no serious side effects.

research Comparison of Finasteride Versus Flutamide in the Treatment of Hirsutism

75 citations , October 1999 in “European journal of endocrinology”

This study found that both finasteride and flutamide effectively reduce hirsutism in women with polycystic ovary syndrome or idiopathic hirsutism, but flutamide was more effective.

A Prospective Randomized Trial Comparing Low Dose Flutamide, Finasteride, Ketoconazole, and Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism

research A Prospective Randomized Trial Comparing Low Dose Flutamide, Finasteride, Ketoconazole, and Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism

113 citations , April 1999 in “The Journal of Clinical Endocrinology and Metabolism”

This study found that all four treatments—flutamide, finasteride, ketoconazole, and EE-CPA—significantly reduced hirsutism, but EE-CPA and flutamide appeared most effective, with varying effects on androgen levels and side-effect profiles.

research Comparison of Cyproterone Acetate Plus Ethinyl Estradiol and Finasteride in the Treatment of Hirsutism

49 citations , June 1998 in “Journal of Endocrinological Investigation”

In this study, both cyproterone acetate-estrogen combination (Diane®) and finasteride were effective in reducing hirsutism, but Diane® showed greater long-term efficacy and cost-effectiveness.

research Hirsutism

67 citations , January 1997 in “Lancet”

This article discusses the causes of hirsutism, identifying increased androgen production and heightened skin sensitivity, and provides no new clinical results.

research Treatment of Hirsutism by Finasteride and Flutamide in Women with Polycystic Ovary Syndrome

38 citations , January 1997 in “Gynecological Endocrinology”

This study found that both finasteride and flutamide effectively reduced hirsutism in women with polycystic ovary syndrome, decreasing the Ferriman-Gallwey score and hair diameter without significant side effects.

Outcome of Long-Term Treatment with the 5α-Reductase Inhibitor Finasteride in Idiopathic Hirsutism: Clinical and Hormonal Effects During a 1-Year Course of Therapy and 1-Year Follow-Up

research Outcome of Long-Term Treatment with the 5α-Reductase Inhibitor Finasteride in Idiopathic Hirsutism: Clinical and Hormonal Effects During a 1-Year Course of Therapy and 1-Year Follow-Up

75 citations , November 1996 in “Fertility and Sterility”

This study found that finasteride effectively reduced hirsutism in women during 12 months of treatment, with some effects persisting in the majority after stopping the medication.

research Finasteride in the Treatment of Hirsutism: New Therapeutic Perspectives

50 citations , July 1996 in “Fertility and Sterility”

This study found that finasteride significantly reduced hirsutism scores in women with idiopathic hirsutism and PCOS, despite no changes in serum androgen levels.

research Finasteride

187 citations , January 1994 in “The New England Journal of Medicine”

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.