Clinical Application of 5α-Reductase Inhibitors

    March 2001 in “ Journal of endocrinological investigation ”
    A Cilotti, Giovanna Danza, Mario Serio
    From the encyclopedia
    Finasteride →

    Frontline, gold standard treatment for combatting androgenic alopecia

    Dutasteride →

    Heavy duty finasteride that comes with higher risks

    Vitamin D →

    vitamin you should probably be taking for general health might also help your hair a little

    Image
    Studysummary This review discusses the use of 5α-reductase inhibitors, particularly finasteride, for treating conditions like benign prostatic hyperplasia, male baldness, and hirsutism, and reports no new clinical results. Our plain-language summary of this paper — not a Tressless recommendation.
    The review article discussed the clinical applications of 5α-reductase inhibitors, particularly finasteride, which had been extensively used for treating benign prostatic hyperplasia (BPH) and male baldness, showing a 50% objective response in baldness treatment. In women, finasteride was used in controlled trials for hirsutism with favorable outcomes. The article suggested that dual inhibitors, like dutasteride, might be more effective for BPH and baldness and potentially for preventing prostate cancer. Pure type 1 5α-reductase inhibitors were considered ideal for treating acne and hirsutism. The study highlighted the importance of enzyme selectivity and the potential for combining treatments, such as vitamin D3 analogues, to enhance therapeutic outcomes.
    Discuss this study in the Community →

    Research cited in this study

    13 / 13 results