Untargeted Metabolomics and Steroid Signatures in Urine of Male Pattern Baldness Patients After Finasteride Treatment for a Year

    August 2021 in “ Journal of The American Academy of Dermatology ”
    Ji-Hoon Lim, Yura Lee, Eunju Im, Haksoon Kim, Jeongae Lee, Han Bin Oh, Ki-Jung Paeng, Min H. Kang, Soon Young Kwon, Woo-Young Sim, Bark-Lynn Lew
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    Studysummary This article discusses metabolomics in the context of finasteride treatment for male pattern baldness and reports no new clinical results.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    The study investigated the effects of finasteride treatment on male pattern baldness (MPB) by analyzing metabolomics and steroid signatures in the urine of patients over a year. Finasteride, which inhibits the 5-alpha reductase enzyme and blocks dihydrotestosterone (DHT) production, was found to impact the levels of DHT and testosterone (T) in patients. The research aimed to provide a comprehensive understanding of the metabolic changes associated with finasteride treatment in MPB patients.
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