Management of Male Pattern Hair Loss

July 2001 in “ PubMed ”

Rodney Sinclair

androgenetic alopecia 5 alpha-reductase type 2 inhibitor finasteride camouflage agents surgical options medical treatments AGA Propecia

TLDR Finasteride helps manage male hair loss, but realistic expectations and support are crucial.

The management of androgenetic alopecia (AGA) was significantly impacted by the introduction of the 5 alpha-reductase type 2 inhibitor, finasteride. However, successful management also required understanding the roles of camouflage agents, surgical options, and other medical treatments. Since no treatment completely reversed baldness, it was crucial to set realistic expectations for patients regarding the outcomes of any intervention. Patient counseling and support were also important components of the management strategy.

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Male androgenetic alopecia is commonly treated with topical minoxidil and oral finasteride, both requiring continuous use. Other options include hair restoration surgery, dutasteride, light therapy, and camouflaging agents.

community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.

in Research/Science 138 upvotes 6 months ago

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

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Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp

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