The Biochemical and Phenotypic Characterization of Females Homozygous for 5 Alpha-Reductase-2 Deficiency

    Melissa D. Katz, Li‐Qun Cai, Yuan‐Shan Zhu … Julianne Imperato‐McGinley
    Studysummary In this study, females with 5 alpha-reductase-2 deficiency exhibited decreased body hair, normal sebum production, and delayed menarche, suggesting a role for DHT in hair growth and menstrual function.
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    Research cited in this study 3

    1. A Prospective Randomized Trial Comparing Finasteride to Spironolactone in the Treatment of Hirsute Women The Journal of Clinical Endocrinology and Metabolism · 1995
    2. Effects of Finasteride, a 5 Alpha-Reductase Inhibitor, on Circulating Androgens and Gonadotropin Secretion in Hirsute Women The Journal of Clinical Endocrinology and Metabolism · 1994
    3. Structure of Human Type II 5 Alpha-Reductase Gene Endocrinology · 1992