Interaction of Chronic Ethanol Exposure and Finasteride: Sex and Strain Differences

    Deborah A. Finn, Season L. Long, Michelle A. Tanchuck, John C. Crabbe
    Image of study
    TLDR Finasteride reduces alcohol withdrawal effects, especially in female mice.
    This study from 2004 investigated the interaction between chronic ethanol exposure and finasteride, a drug used to treat hair loss, in male and female mice. The researchers found that finasteride pretreatment decreased the severity of ethanol withdrawal in mice, with the reduction being more pronounced in female D2 mice. The study also suggested that finasteride may alter ethanol pharmacokinetics, which could explain its effect on withdrawal severity. However, additional studies are needed to determine the mechanism by which finasteride alters chronic ethanol withdrawal severity.
    Discuss this study in the Community →

    Research cited in this study

    3 / 3 results

    Related Community Posts Join

    6 / 1000+ results

      community Don’t make the same mistake I did

      in Treatment  111 upvotes 3 years ago
      User noticed hair thinning at 26 and used minoxidil for 2 years with slight improvement. Stopping minoxidil led to dramatic hair loss, and others shared similar experiences, suggesting minoxidil and finasteride should be used consistently for best results.

      community My experience with Pyrilutamide

      in Update  43 upvotes 2 years ago
      Two different experiences of using Pyrilutamide, a hair loss treatment, which caused headaches that took around a week to subside in both cases. Other users offered insight into their own experiences with the treatment or suggested alternate treatments such as RU58841 and Minoxidil.

      community 3 and a bit months on topical min & fin

      in Progress Pictures  516 upvotes 9 months ago
      A user shared progress pictures showing significant hair regrowth after 3 months using a topical foam with 5% Minoxidil and 0.25% Finasteride. They plan to add derma rolling to their routine.

    Related Research

    5 / 5 results