27 citations
,
April 2007 in “European Journal of Pharmacology” Progesterone increases alcohol tolerance and withdrawal anxiety, while DHEAS prevents them.
12 citations
,
December 2009 in “Neuroscience” GABAergic steroid precursors reduce ethanol withdrawal symptoms in certain mice.
54 citations
,
August 2005 in “Alcohol” This study found that acute finasteride treatment decreased ethanol intake in male C57BL/6J mice, whereas chronic treatment showed diminished effects, implying compensatory changes in neurosteroid modulation.
83 citations
,
January 2004 in “Pharmacology & Therapeutics” This review explores the potential role of pregnane neurosteroids in modulating alcohol withdrawal symptoms, suggesting a therapeutic target for treating alcohol dependence, but reports no new clinical results.
21 citations
,
June 2005 in “Alcoholism: Clinical and Experimental Research” This study found that finasteride affected ethanol withdrawal severity differently in WSP and WSR lines, with more modulation seen in the WSP line.