Finasteride Blocks Progesterone Synthesis in MA-10 Leydig Tumor Cells

October 1993 in “ Endocrinology ”

D.A. Freeman

Studysummary In this study, finasteride inhibited progesterone synthesis in mouse-derived MA-10 Leydig tumor cells by blocking cholesterol side-chain cleavage, but human and rat cells showed minimal sensitivity.

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