This narrative review discusses the historical and current use of platelet-rich plasma in dermatology and reports no new clinical results; the authors suggest it may reduce the need for invasive procedures.
August 2024 in “Frontiers in Nutrition” In this study, higher dietary antioxidant intake was linked to a decreased risk of androgenic alopecia, while higher dietary inflammatory intake increased the risk, especially among women, although these links were influenced by metabolic syndrome presence.
August 2024 in “Journal of Clinical Medicine” This review examines quality control in preparing platelet-rich plasma, highlighting knowledge gaps in its clinical efficacy and safety, but reports no new clinical results.
July 2024 in “Anais Brasileiros de Dermatologia” PRP injections can increase hair density in people with androgenic alopecia.
2 citations
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May 2024 in “Cureus” This study found that both single and double spin platelet-rich plasma methods significantly reduced chronic ulcer surface area, with single spin showing notable healing improvements.
December 2023 in “PubMed” This study found that both single- and double-spin PRP preparation methods significantly increased thrombocyte counts and improved hair parameters in males with androgenetic alopecia, with the single-spin method showing a more significant increase in thrombocyte count.
June 2023 in “Skin Research and Technology” This study concluded that, in male patients with mild-to-moderate androgenetic alopecia, injections of PRP prepared by an automated method combined with topical 5% minoxidil were effective and safe, showing superior clinical efficacy and patient satisfaction compared to PRP alone.
June 2023 in “Journal of Cosmetic Dermatology” This study found that a combination therapy of autologous platelet-rich plasma and non-cross-linked hyaluronic acid increased hair density significantly in women with female androgenetic alopecia, without serious adverse effects.
May 2023 in “International Journal of Trichology” In this study, PRP therapy did not show significant effectiveness in treating androgenetic alopecia in patients over a 6-month period, with 45% of participants reporting no improvement in hair growth, although adverse effects were minimal and non-serious.
April 2023 in “Medizinische Genetik” This review discusses the current status of genetic research on male-pattern hair loss and reports no new findings, outlining significant achievements and future challenges in understanding its biology and treatment.
6 citations
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August 2022 in “Dermatologic therapy” This study reports that platelet-rich plasma therapy resulted in temporary hair growth in patients with stabilized Central Centrifugal Cicatricial Alopecia.
2 citations
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April 2022 in “Indian Journal of Dermatology, Venereology and Leprology” This pilot study suggests that platelet-rich plasma may be a promising treatment for chronic telogen effluvium with good safety, and cost-effective preparation methods may be reliable alternatives to more expensive ones.
January 2022 in “Journal of Cosmetic Dermatology” This study found that PRP injections, prepared using a digital centrifuge with a large-sized sodium citrate tube at low centrifugation speed, significantly improved hair thickness and terminal hair percentage in women with pattern hair loss, with similar results across different preparation methods.
2 citations
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December 2021 in “Journal of Cosmetic Dermatology” This review analyzes existing literature on platelet-rich plasma for hair loss, discussing its mechanisms and preparation, but reports no new clinical results and highlights the inconsistency of current evidence.
15 citations
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October 2020 in “Journal of Investigative Dermatology Symposium Proceedings” This review discusses the potential use of platelet-rich plasma for treating alopecia areata but reports no new experimental findings, noting the need for standardized protocols and larger studies to evaluate its efficacy.
10 citations
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September 2020 in “Archives of Dermatological Research” Both methods improve hair density and thickness; double-spin may be more effective.
6 citations
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July 2018 in “PubMed” In this study, a combination therapy involving oral finasteride, oral and topical minoxidil, and injectable treatments led to significant improvements in hair growth for Asian men with androgenetic alopecia, with high patient satisfaction and minimal complications over a period of 6 to 12 months.
24 citations
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November 2017 in “Aesthetic Plastic Surgery” In this study, researchers found that homologous PRP (h-PRP) significantly increased hair density more than both nonactivated (n-PRP) and activated (a-PRP) autologous PRP in patients with androgenetic alopecia, suggesting h-PRP as a potentially more effective treatment option for hair loss.
136 citations
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February 2017 in “International Journal of Molecular Sciences” This study observed that autologous platelet-rich plasma treatment improved hair count and density in areas with androgenetic alopecia compared to placebo, with differing outcomes based on the PRP collection device used.
9 citations
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January 2017 in “International Journal of Trichology” This review discusses various classification systems for male-pattern hair loss, comparing their detail, practicality, and reproducibility, and reports no new clinical outcomes.
87 citations
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September 2016 in “Dermatologic Surgery” This study found that platelet-rich plasma did not significantly improve hair mass index or hair count in women with female androgenetic alopecia, though some patients perceived benefits in hair quality.
270 citations
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March 2012 in “Dermatologic Surgery” This study found that autologous platelet-rich plasma increased hair growth potential by enhancing dermal papilla cell proliferation and stimulating key signaling pathways in both cell cultures and mice models.
