The History and Current Status of Platelet-Rich Plasma Therapy in Dermatology

August 2024 in “ Cureus ”

M. Arias Rodríguez, Harvey N. Mayrovitz

platelet-rich plasma PRP hair loss wrinkles scars ulcers skin pigmentation disorders anti-inflammatory growth factors

Studysummary This narrative review discusses the historical and current use of platelet-rich plasma in dermatology and reports no new clinical results; the authors suggest it may reduce the need for invasive procedures.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

Platelet-rich plasma (PRP) therapy has significantly advanced in dermatology, effectively treating conditions like alopecia, ulcers, skin rejuvenation, acne, and scars. Studies show PRP promotes hair growth in androgenic alopecia and alopecia areata, enhances collagen production for better skin texture, and improves scar healing when combined with microneedling or subcision. PRP also aids in healing chronic ulcers and repigmenting vitiligo patches, reducing the need for invasive procedures by leveraging its anti-inflammatory properties and growth factors for tissue regeneration.

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research Platelet-Rich Plasma in Alopecia Areata: A Case Report With a Mini Review of Literature

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In this study, a 46-year-old patient with alopecia areata experienced successful hair regrowth and improved quality of life after three monthly applications of platelet-rich plasma, which the authors noted is a relatively effective, safe, and minimally invasive treatment option.

research Successful Treatment of Alopecia Areata Barbae with Platelet-Rich Plasma

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This case report suggests that platelet-rich plasma injections may offer a new and potentially effective treatment for alopecia areata barbae, as demonstrated by notable hair regrowth in one patient over one year.

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research Role of Platelet-Rich Plasma in Chronic Alopecia Areata: Our Centre Experience

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This study found that platelet-rich plasma may have a role in treating chronic alopecia areata, but more long-term follow-up studies are needed to confirm its effectiveness and success rate.

research Androgenetic Alopecia

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research Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth

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This study found that autologous platelet-rich plasma increased hair growth potential by enhancing dermal papilla cell proliferation and stimulating key signaling pathways in both cell cultures and mice models.

research The Role of Platelet Plasma Growth Factors in Male Pattern Baldness Surgery

251 citations , October 2006 in “Plastic and reconstructive surgery/PSEF CD journals”

In this study, platelet plasma growth factors from patients' autologous plasma improved follicular unit yield in baldness surgery by 15.1% compared to control areas.