Different Platelet-Rich Plasma Preparation Protocols in Female Pattern Hair Loss: Does It Affect the Outcome? A Pilot Study

    January 2022 in “ Journal of Cosmetic Dermatology
    Nayera H. Moftah, Nour Taha, Alshaymaa M Alhabibi, Mervat Hamdino
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    TLDR The best way to prepare Platelet-Rich Plasma for hair loss treatment in women is using a digital centrifuge, large sodium citrate tubes, and low speed spinning. This method is safe and effectively increases hair thickness and growth.
    The pilot study, involving 40 female patients with Female Pattern Hair Loss (FPHL), aimed to optimize standard Platelet-Rich Plasma (PRP) preparation protocols and evaluate its clinical efficacy in FPHL. The patients were divided into 4 groups, each receiving 3 sessions of monthly intradermal injection of PRP prepared by different methods. The results showed a significant increase in platelet count in PRP prepared by a combination of digital centrifuge, large-sized sodium citrate tube, and low centrifugation speed (900 rpm). All patients showed a significant increase in the percentage of terminal hair and average width of hair after treatment, without a significant difference between the studied groups. The study concluded that digital centrifuge, large-sized sodium citrate tubes, and a single spin with low centrifugation speed (900 rpm) were ideal for PRP preparation, and PRP is an effective and safe modality in FPHL therapy.
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