Different Platelet-Rich Plasma Preparation Protocols in Female Pattern Hair Loss: Does It Affect the Outcome? A Pilot Study

January 2022 in “ Journal of Cosmetic Dermatology ”

Nayera H. Moftah, Nour Taha, Alshaymaa M Alhabibi, Mervat Hamdino

platelet-rich plasma PRP Female Pattern Hair Loss FPHL intradermal injection digital centrifuge sodium citrate tube centrifugation speed terminal hair

TLDR The best way to prepare Platelet-Rich Plasma for hair loss treatment in women is using a digital centrifuge, large sodium citrate tubes, and low speed spinning. This method is safe and effectively increases hair thickness and growth.

The pilot study, involving 40 female patients with Female Pattern Hair Loss (FPHL), aimed to optimize standard Platelet-Rich Plasma (PRP) preparation protocols and evaluate its clinical efficacy in FPHL. The patients were divided into 4 groups, each receiving 3 sessions of monthly intradermal injection of PRP prepared by different methods. The results showed a significant increase in platelet count in PRP prepared by a combination of digital centrifuge, large-sized sodium citrate tube, and low centrifugation speed (900 rpm). All patients showed a significant increase in the percentage of terminal hair and average width of hair after treatment, without a significant difference between the studied groups. The study concluded that digital centrifuge, large-sized sodium citrate tubes, and a single spin with low centrifugation speed (900 rpm) were ideal for PRP preparation, and PRP is an effective and safe modality in FPHL therapy.

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Research cited in this study

11 / 11 results

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PRP treatment improves hair density and thickness for alopecia, but needs more research.

research Platelet-Rich Plasma for Androgenetic Alopecia: A Review of the Literature and Proposed Treatment Protocol

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PRP shows promise for hair loss treatment, with three initial monthly injections and maintenance every 3-6 months.

research A Mechanistic Model of Platelet-Rich Plasma Treatment for Androgenetic Alopecia

60 citations, September 2016 in “Dermatologic Surgery”

PRP treatment may stimulate hair growth by promoting blood vessel formation, increasing growth factors, and preventing cell death.

research Association of Metabolic Syndrome With Female Pattern Hair Loss in Women: A Case-Control Study

21 citations, April 2016 in “International Journal of Dermatology”

Metabolic syndrome linked to female hair loss; waist size and high blood pressure important factors.

research The Effect of Different Speeds of Centrifugation on Platelet-Rich Plasma Preparation

2 citations, September 2015 in “Journal of the Egyptian Women's Dermatologic Society (Print)”

Different centrifugation speeds change the quality of platelet-rich plasma.

research Platelet-Rich Plasma for Androgenetic Alopecia

107 citations, August 2014 in “Dermatologic Surgery”

PRP injections improve hair thickness for baldness.

A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

research A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

205 citations, April 2013 in “British Journal of Dermatology”

Platelet-rich plasma treatment significantly increased hair regrowth and decreased discomfort in alopecia patients, making it a potentially better and safer treatment option.

research The Importance of Trichoscopy in Clinical Practice

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Trichoscopy is a valuable tool for diagnosing and managing hair and scalp disorders.

research Letter: Platelet-Rich Plasma for Treating Male Pattern Baldness

36 citations, December 2012 in “Dermatologic Surgery”

Injecting platelet-rich plasma (PRP) can increase hair growth rate and density in male pattern baldness.

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research Different Platelet-Rich Plasma Preparation Protocols in Female Pattern Hair Loss: Does It Affect the Outcome? A Pilot Study

January 2022 in “Journal of Cosmetic Dermatology”

The best way to prepare Platelet-Rich Plasma for hair loss treatment in women is using a digital centrifuge, large sodium citrate tubes, and low speed spinning. This method is safe and effectively increases hair thickness and growth.